Publications by authors named "Kinza Hasham"

Article Synopsis
  • Influenza is a highly contagious virus that can make people really sick and is a big concern for public health around the world.
  • The Influenza B virus causes yearly outbreaks, and scientists study it using a method called reverse genetics to understand how it spreads and causes illness.
  • Reverse genetics allows researchers to change the virus's genes, helping them create better vaccines and understand how different virus strains behave so they can protect people from future outbreaks.
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Influenza B virus (IBV) significantly impacts the health and the economy of the global population. WHO global health estimates project 1 billion flu cases annually, with 3 to 5 million resulting in severe disease and 0.3 to 0.

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Background: Hepatocellular carcinoma (HCC) adopts several tumor immune escape mechanisms; therefore, it has the potential to be targeted by immunotherapy. Indoleamine 2, 3-dioxygenase (IDO) is an immunosuppressive enzyme that has been observed to be overexpressed in HCC patients with poor prognoses. Bridging integrator 1 (Bin1) loss promotes immune escape in cancer by deregulating IDO.

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