Development of polymer monolith-MOF hybrid via surface functionalization for bioanalytical sciences.

Monoliths are versatile materials with diverse applications, and their performance can be enhanced through modifications, including the use of metal-organic frameworks (MOFs). Modified monoliths improve separation and analytical processes in various fields, with different modification methods offering distinct benefits and challenges. Directly adding MOF crystals to the polymerization mixture is straightforward and time effective, but it often results in poor dispersion and compositional heterogeneity, which compromises consistency and reproducibility, particularly in bioanalytical applications.