Soluble urokinase plasminogen activator receptor in one-year prediction of major adverse cardiac events in patients after first myocardial infarction treated with primary percutaneous coronary intervention.

Introduction: Soluble urokinase plasminogen activator receptor (suPAR) level reflects the general condition of the organism and was proved to give independent information in risk stratification of patients. The aim of this study was to assess the usefulness of suPAR in the prediction of adverse cardiac events in patients with first myocardial infarction (MI) undergoing primary percutaneous coronary intervention. Additionally, the diagnostic power of suPAR was assessed.

Clinical and prognostic usefulness of soluble urokinase plasminogen activator receptor in hemodialysis patients.

Purpose: Considering its prognostic usefulness and the relationship with chronic kidney disease, we analyzed the clinical utility of soluble urokinase plasminogen activator receptor (suPAR) in end-stage renal disease patients undergoing hemodialysis treatment. We focused on the association between suPAR levels and clinical outcomes, especially those related to cardiovascular events and mortality as well as the effect of hemodialysis on the protein levels.

Methods: We enrolled 64 patients.

[Accidental severe poisoning with methemoglobinogenic substance: A case report].

A 45-year-old male patient was admitted to the Regional Poison Center because of poisoning with dimethyloaniline contained in a toxic resin-curing dimethyl aniline-based formulation ingested inadvertently. Intoxication happened at workplace. The patient was then transferred to the Toxicology Clinic, where he stayed for 3 weeks.

Analysis of Separation of White Blood Cells in Peripheral Blood as an Indicator of MPO Deficiency.

The purpose of this study was to analyze the white blood cell (WBC) percentage pattern of patients with myeloperoxidase disorder. During the 18 months of routine work, 36 blood samples were found with disorders of myeloperoxidase activity: 12 cases of total myeloperoxidase (MPOt) deficiency and 24 cases of partial myeloperoxidase (MPOp) deficiency. In the group with MPOp, according to the results, monocytes (MONO) were the dominant population 33.

[The problem of re-confirming the driving licence in the practice of the clinical department].

Background: The standpoint published by the National Consultant in the Field of Occupational Medicine obliges physicians to send, to institutions responsible for traffic safety, the information on individuals who, for medical reasons, should not be permitted to drive motor vehicles. This situation is a source of a conflict: on the one hand the medical profession is a profession of public trust; on the other the doctor, when performing his/her official duties, is obliged to safeguard the wellbeing of the general population and, therefore, is expected to take suitable measures (including administrative) if he/she is in the possession of an information that something or someone may offer a threat to traffic safety.

Material And Methods: On the basis of the existing legal regulations as well as author's own experiences, it has been attempted to standardize clinical and certifying procedures to be used in cases when an individual (a driver candidate or a current driver) is reasonably suspected to be encumbered with a characteristic that precludes him/her from being granted permission to drive motor vehicles.

Waist circumference, ghrelin and selected adipose tissue-derived adipokines as predictors of insulin resistance in obese patients: preliminary results.

Background: The aim of the study was to estimate the association between anthropometric obesity parameters, serum concentrations of ghrelin, resistin, leptin, adiponectin and homeostasis model assessment (HOMA-IR) in obese non-diabetic insulin-sensitive and insulin-resistant patients.

Material/methods: Study subjects included 37 obese (body mass index [BMI] ≥ 30 kg/m2) out-clinic patients aged 25 to 66 years. Insulin resistance was evaluated by HOMA-IR.

Comparison of microscopic methods for evaluating platelet adhesion to biomaterial surfaces.

Microscopic methods usable for sample surface imaging and subsequent qualitative and quantitative evaluation of platelet adhesion to the surface of the biomaterial studied were compared. It was shown, making use of the samples of medical steel (AISI 316L), that such tools as surface imaging with scanning electron microscopy (SEM), glutaraldehyde induced fluorescence technique (GIFT) and metallurgical microscopy (MM) are equivalent in evaluating surface platelet adhesion. The importance of biological variability of blood samples for a proper result assessment and the necessity of using internal standards were also considered.