Skin decontamination by low-temperature atmospheric pressure plasma jet and dielectric barrier discharge plasma.

Background: Over the past few years, plasma medicine has become an important field in medical science. Cold plasma has proven anti-inflammatory, antimicrobial and antineoplastic effects.

Aim: To test the decontamination power of two cold plasma sources [low-temperature atmospheric pressure plasma jet (APPJ) and dielectric barrier discharge plasma (DBD)] in vivo on human fingertips.

Cold plasma is well-tolerated and does not disturb skin barrier or reduce skin moisture.

Background: Cold plasma, a new treatment principle in dermatology based on ionic discharge delivering reactive molecular species and UV-light, exhibits strong antimicrobial efficacy in vitro and in vivo. Before implementing plasma as new medical treatment tool, its safety must be proven, as well as assessing skin tolerance and patient acceptance.

Patients And Methods: We investigated the plasma effects of three different plasma sources (pulsed, non-pulsed atmospheric pressure plasma jet (APPJ) and a dielectric barrier discharge (DBD)) on the transepidermal water loss (TEWL) and skin moisture after treating the fingertips of four healthy male volunteers.

Atmospheric plasma enhances wettability and cell spreading on dental implant metals.

Objectives: Treatment regimens, which predictably support re-osseointegration of implants with peri-implantitis, are needed. Increased wettability may be an important factor for re-osseointegration. In this study, a cold atmospheric pressure gas-discharge plasma was applied to reduce water contact angles on titanium discs with different surface topography and to improve the spreading of osteoblastic cells.

Antimicrobial efficacy of non-thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro - proof of principle experiment.

Aim: Dental biofilms play a major role in the pathogenesis of peri-implant mucositis. Biofilm reduction is a pre-requisite for a successful therapy of peri-implant mucosal lesions. In this study, we evaluated the effect of three different plasma devices on the reduction of Streptococcus mutans (S.

The modified HET-CAM as a model for the assessment of the inflammatory response to tissue tolerable plasma.

Plasma medicine is a novel, highly interdisciplinary field of research. Although the knowledge is rare concerning plasma based biomedical mechanisms, correct dosages and treatment times, animal experiments have been carried out. To follow the 3Rs (reduction, refinement, replacement), it is necessary to define methods for the screening of plasma parameters.

Efficacy of chlorhexidine, polihexanide and tissue-tolerable plasma against Pseudomonas aeruginosa biofilms grown on polystyrene and silicone materials.

Background: The formation of biofilms is crucial in the pathogenesis of many acute and subacute microbial infections, including chronic wounds and foreign-body-related infections. Topical antimicrobial therapy with chemical antiseptics or physical treatment with tissue-tolerable plasma (TTP) may be promising to control bacterial infection.

Methods: We assessed the efficacy of 0.

Antiseptic efficacy and tolerance of tissue-tolerable plasma compared with two wound antiseptics on artificially bacterially contaminated eyes from commercially slaughtered pigs.

Aim: To compare the tissue tolerance and efficacy of two wound antiseptics with tissue-tolerable plasma (TTP) on enucleated contaminated eyes from slaughtered pigs in order to draw consequences for the use of TTP on wounds.

Method: The corneas of extracted eyes were contaminated with Staphylococcus aureus or Pseudomonas aeruginosa. One and 10 min after application of 10% povidone (PVP)-iodine and 0.

Antimicrobial efficacy and potential application of a newly developed plasma-based ultraviolet irradiation facility.

A low-pressure mercury vapour discharge tube generating high-intensity ultraviolet (UV) resonance radiation at 254 nm was designed to achieve a nearly simultaneous all-round UV irradiation of products. Testing this 'universal homogeneous ultraviolet (UHUV) irradiation facility' with suspended Bacillus subtilis spores, resulted in a 10(6)-fold reduction in viable count within 30 s applying irradiation energy of 0.3 mW/cm(2).

Self-consistent model of a positive column in a glow discharge under free-flight and collisional regimes of charged-particle motion.

We consider the nonlocal theory of a positive column in a glow discharge in two cases, where the mean free path of charged particles is either greater than the discharge tube radius (the free-flight regime) or much less than the radius (the collisional regime). The great bulk of electrons, which determines the density and the discharge current in the axial direction, appears to be trapped by the radial field of a positive column. The electron flux to the wall, which compensates for the ionization in a volume, is determined by fast electrons with energies of the order of wall potential, which are able to leave in a loss cone.