Morphinan Alkaloids from the Leaves of Alphonsea cylindrica and Their Antibacterial Properties.

A phytochemical study has been carried out on CHCl extract of leaves, resulting in the isolation of three new morphinan alkaloids. They are kinomenine (1: ), -methylkinomenine (2: ), and hydroxymethylkinomenine (3: ). The structures of these compounds were elucidated by extensive spectroscopic analysis (1D and 2D NMR, IR, UV, HRESIMS) and comparison with the data reported in literature for similar alkaloids.