Burden of rodent-borne viruses in rodents and zoonotic risk in human in Cambodia: a descriptive and observational study.

Background: Rodent-borne viruses, including hantaviruses, arenaviruses, and rodent hepatitis virus (HEV-C), pose significant health threats to humans, causing severe diseases such as hepatitis, respiratory illness, and hemorrhagic fevers. In Cambodia, data on these viruses remain limited, and their burdens on human health are unknown. This study investigated the presences of these viruses in rodents and assessed potential human exposure across diverse environmental and socio-economic contexts in Cambodia.

Air sampling accurately captures circulating zoonotic viral diversity emerging from poultry live-animal markets.

Environmental surveillance has emerged as a pivotal strategy for early detection of pathogens that pose threats to humans (1) but has not been utilized for zoonotic agents. In Asia, live-bird markets (LBMs) are key human-animal interfaces for zoonotic virus transmission (2). Traditional sampling strategies are time-consuming, expensive, threaten animal welfare and have significant occupational biosafety risks.

Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia).

Avian influenza virus (AIV) in Asia is a complex system with numerous subtypes and a highly porous wild birds-poultry interface. Certain AIV subtypes, such as H14, are underrepresented in current surveillance efforts, leaving gaps in our understanding of their ecology and evolution. The detection of rare subtype H14 in domestic ducks in Southeast Asia comprises a geographic region and domestic bird population previously unassociated with this subtype.