Publications by authors named "Kimsor Hong"

Article Synopsis
  • - Microglia are specialized immune cells in the central nervous system that help maintain health and respond to injury or disease, playing a key role in neuroinflammation related to neurodegenerative diseases and tumors.
  • - Research suggests that extracellular vesicles can facilitate communication between cells by transporting molecules, which is important for microglial signaling in the nervous system.
  • - The text emphasizes the need to understand how microglia and extracellular vesicles contribute to brain health and disease progression, potentially paving the way for new therapeutic approaches that do not involve direct cell intervention.
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Article Synopsis
  • Autoimmune diseases happen when the body's immune system mistakenly attacks its own healthy cells, causing damage and inflammation.
  • Omega-3 fatty acids, found in foods like fish, might help reduce this inflammation, but scientists aren't sure how effective they are for different autoimmune diseases.
  • A study analyzed 21 previous studies and found that omega-3s seem to help with some autoimmune diseases like rheumatoid arthritis and lupus but didn’t provide clear evidence for their effects on others like psoriasis and type 1 diabetes.
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Background: Human umbilical cord mesenchymal stem cells-derived extracellular vesicles (hUCMSC-EVs) have potent immunomodulatory properties similar to parent cells. This study investigated the therapeutic effects and immunomodulatory mechanisms of hUCMSC-EVs in an experimental lupus nephritis model.

Methods: The hUCMSC-EVs were isolated by using differential ultracentrifugation.

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