[Influence of liver function on stereotactic microwave tissue coagulation therapy for hepatocellular carcinoma].

We studied 21 cases of hepatocellular carcinoma with liver cirrhosis to investigate the influence of liver function on stereotactic microwave tissue coagulation therapy. The cases were divided into three groups by the operation. The first group received only hepatectomy, the second hepatectomy and coagulation therapy for any remaining tumor, and the third group received only coagulation therapy.

Differentiation of breast tumors by ultrasonic tissue characterization.

The ability of ultrasonic tissue characterization to differentiate and classify benign and malignant breast tissues in vivo in patients with palpable breast masses and in vitro in excised breast tissue was evaluated. One-hundred and twenty-four in vivo and 89 in vitro studies were performed using a technique of UTC based on parameters from the power spectrum of backscattered echoes. Sensitivities and specificities for diagnosing carcinoma were 86 and 84% for in vivo studies and 94 and 92% for in vitro studies.

Intraoperative ultrasonography during laparoscopic cholecystectomy.

Intraoperative ultrasonography during laparoscopic cholecystectomy is a new procedure for examining the bile duct. The ultrasonic probe used in this study utilized a 7.5-MHz convex array designed for easy insertion through a 10-mm cannula.

Age determination of experimental venous thrombi by ultrasonic tissue characterization.

Purpose: The ability of ultrasonic tissue characterization based on radiofrequency signal processing to detect compositional differences in thrombi of varying ages was evaluated in vivo.

Methods: Thrombi were produced in 49 jugular veins of 26 anesthetized 18 to 20 kg pigs by partial ligation and application of direct electric current. Thrombi were imaged 30 minutes after formation and 1, 7, and 14 days later with a color Doppler ultrasound scanner that identified the thrombi, and acquired radio frequency data for ultrasonic tissue characterization analysis.

Effect of perfusion and blood content on ultrasonic backscattering of liver tissue.

The purpose of this study was to determine the effect of blood flow perfusion and red cell content on ultrasonic scattering by liver tissue. Data acquisition for ultrasonic tissue characterization (UTC) employing analysis of the backscattered echoes from the power spectrum was obtained from the same region of pig liver tissue under four conditions: 1) normal perfusion in situ, 2) ischemia in situ in the living pig, 3) ischemia in situ immediately postmortem, and 4) immediately after excision of the liver. Discriminant function analysis was used to evaluate differences in the two basic parameters from the normalized power spectrum: slope and intercept.

[An experimental study of ethanol injection on VX2 liver cancer].

Ethanol injection therapy for rabbit VX2 cancer of the liver was performed to measure the extent of ethanol infiltration using normal hepatic tissue as control, to observe the serial histological findings after ethanol injection, and to determine the influence of the ethanol on survival days with VX2 cancer of the liver. The necrotic area caused by ethanol showed a significant dose-dependent correlation in the range of 0.1-1.

Direct observation of the portal vein interior by intra-operative angioscopy in the dog and man.

The purpose of this study was to develop the technique of intra-operative portal angioscopy using a portal angioscope, and to demonstrate its potential use in the therapy for patients with hepatocellular carcinoma (HCC) bearing a portal thrombus. Portal angioscopes, Olympus BF3C10 and CHFP10 of a diameter of 3.5 mm and 4.

[Intra-arterial infusion chemotherapy of liver metastases in colorectal cancer].

We report the complications and the results of intra-arterial infusion chemotherapy (IAIC) for liver metastases in colorectal cancer. Fifteen synchronous liver metastases and 11 metachronous liver metastases were treated from September 1986 to February 1989. Eight cases had H1 (metastases in one lobe only), 11 cases H2 (a few scattered metastases in both lobes) and 7 cases had H3 (numerous metastases in both lobes).