Exploring interests: A pathway to ikigai and eudaimonic well-being among people with serious mental illness.

Objective: Ikigai is a Japanese concept of a life worth living and related to eudaimonic well-being. Supporting the pursuit of is of central importance to recovery-oriented psychiatric rehabilitation for people with serious mental illnesses (SMI). While research suggests that work, leisure, and social relationships are potential sources of , people with SMI have restricted access to these as they encounter systemic barriers to participating in such activities.

Solvent-Dependent Conformational Switching of N-Methyl-N,N'-diarylsquaramide.

,'-Diarylsquaramide and ,'-dialkylsquaramide are conformationally stable linkers with extended (trans, trans) and folded (cis, cis) structures, respectively, independently of external conditions. Here, we show that -monomethylated ,'-diarylsquaramides generally take a (trans, cis) structure in the crystal but show a solvent-dependent conformational equilibrium in solution. In particular, the stable conformer of -methyl-,'-bis(1-naphthyl)squaramide () changes depending upon the solvent.

Conceptualizing participation in the community mental health context: Beginning with the Clubhouse model.

Purpose: Although participation is key to community mental health, the concept remains elusive. The study explored a conceptualization of participation in the community-based mental health agencies context from a first-person perspective, using the Clubhouse model as an example.

Methods: Qualitative data, collected from 21 Clubhouse service users through three focus groups (1 UK and 2 US) for primary analysis and secondary data from 104 individual interviews, were analysed using a grounded theory approach.

Construction of Aromatic Multilayered Structures Based on the Conformational Properties of N,N'-Dimethylated Squaramide.

Squaramide is a highly rigid four-membered ring system bearing two carbonyl and two amino groups, and its derivatives have found applications in many fields. We synthesized several N,N'-dimethylated oligosquaramides linked via phenyl groups, and investigated their structures in the crystalline state and in solution. Compounds 1, 2 (bissquaramides), and 13 (trissquaramide) exist as folded structures in the crystalline state, in which the aromatic rings are located in a face-to-face position.

"Pushing the Boat Out": A Meta-synthesis of How Members, Staff and Family Experience the Clubhouse Model.

To explore how member, staff, and family experience the contributions of the clubhouse model to outcomes for adults with severe mental illness. Given the significant role social and vocational arenas play in promoting wellbeing, irrespective of health status, explorations of the role such arenas can play in helping individuals accomplish their life and vocational goals may be useful in guiding policy and practice. A metaethnography was conducted using 11 qualitative studies published between 2000 and 2015.

Sense of clubhouse community belonging and empowerment.

Background: While the neighborhood community literature well documents a link between participation in supportive and effective community groups or activities and empowerment, there is as yet little empirical evidence of this relationship in the context of community mental health programs.

Aim: The primary purpose of the study was to examine the relationship between sense of community belonging and empowerment among members of mental health clubhouses.

Methods: A secondary analysis using a hierarchical regression model was conducted on cross-sectional structured interview data collected through a self-report questionnaire from 102 clubhouse members from six clubhouses in the United States and Finland.

Meanings associated with the core component of clubhouse life: the work-ordered day.

Despite the clubhouse model's 60-year existence internationally, the central nature of its core program, the "work-ordered day" (WOH) (Beard et al. in Psychosocial Rehabilitation Journal 5:47-53, 1982), is not well understood; hence, the primary focus of the present study was to explore members' experiences of the nature and meaning of the WOH. The study drew on qualitative interview data collected in 2009-2013 through open-ended questions and probes with 102 members and 24 staff from 5 Clubhouse International-certified clubhouses (2 US and 3 Finnish).

Dentilisin involvement in coaggregation between Treponema denticola and Tannerella forsythia.

Periodontitis arises from a biofilm consisting of gram-negative anaerobic rods and spirochetes. Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, termed the Red complex, have been co-isolated with high frequency from chronic periodontitis lesions, and these microorganisms are thought to be major pathogens of the disease. Coaggregation is an important strategy in the colonization of dental plaque biofilm by these bacteria.

Surnames and Gender in Japan: Women’s Challenges in Seeking Own Identity.

[[Japansurnamefamilygendermarriagelaw ]] Strongly influenced by the previous Meiji Civil Code that shaped people’s perceptions about the traditional Japanese family, postwar Japanese society has not fully guaranteed gender equality, and whether to legally allow the dual-surname system is one of the major legal and political debates in Japanese society. To understand the tension between the traditional Japanese family emphasized in the previous Meiji Civil Code and gender equality emphasized in the current Japanese law, this study explored the surname system in Japan by reviewing historical trends, recent surveys, political debates, and comparing with other nations. This study illustrated that the surname was not attached to the family lineage and membership as today in the past, and symbolic significance of the surname has changed through the course of Japanese history.

Limitations for measuring religion in a different cultural context - the case of Japan.

The article points out the limitations in surveys measuring religiosity and spirituality using the measures developed in Christian or Western contexts. Japanese people think of religion (shūkyō) as revealed religion such as Christianity that has specific doctrinal belief and faith. Through their history of religious regulation, Japanese people came to consider themselves "non-religious" as a way of survival, not to be punished by political authorities and not to be stigmatized in their community.

Aging in rural Japan--limitations in the current social care policy.

Owing to equal and increased opportunities for education and employment, today's trend in Japanese marriages is characterized by late and less frequent marriage. This paper discusses unavoidable diversity in rural families to point out the anticipated consequences of aging in rural areas and to discuss limitations in current public social care policies. Specifically, the averaged proportion of never-married and single persons at ages 45 to 49 and 50 to 54 in legally recognized depopulated cities, towns, and villages in Japan is calculated to illustrate the expected diversity in families in rural depopulated areas.

Social integration and healthy aging in Japan: how gender and rurality matter.

The current study analyzed the 1999 and 2001 waves of the Nihon University Japanese Longitudinal Study of Aging. Two measures of social integration were associated with lower risks of being physically disabled or depressed at Wave 1 and with a lower risk of progressing into deeper levels of physical disability and depression by Wave 2. Ceteris paribus, compared to elderly urbanites, elderly ruralites had a much higher risk of being physically disabled but much lower odds of being depressed.

Characterization of mutations affecting embryonic hematopoiesis in the medaka, Oryzias latipes.

In a genetic screen for mutations affecting organogenesis in the medaka, Oryzias latipes, we identified eight mutants with defects in embryonic hematopoiesis. These mutations were classified into seven complementation groups. In this paper, we characterize the five mutants that were confirmed in the next generation.

Misexpression of mouse porcupine isoforms modulates the differentiation of P19 embryonic carcinoma cells.

Drosophila porcupine (porc) encodes an ER membrane protein that is required for the processing of the Drosophila Wnt family. Homologs of porc have been identified in various multicellular organisms and have been implicated in the biosynthesis of Wnt proteins. In contrast to Drosophila, vertebrates generate four different porc mRNAs (A-D) by alternative splicing.

Spatial distribution of mDLG6 mRNA in embryonic and adult mouse brain.

We have isolated mouse DLG6 (mDLG6) cDNA clones by RT-PCR and then by using the RT-PCR products to screen a mouse brain cDNA library. The deduced amino acid sequence of mDLG6 shows 79.2% and 82.

Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.

Wnt is a family of cysteine-rich secreted glycoproteins, which controls the fate and behavior of the cells in multicellular organisms. In the absence of Drosophila segment polarity gene porcupine (porc), which encodes an endoplasmic reticulum (ER) multispanning transmembrane protein, the N-glycosylation of Wingless (Wg), one of Drosophila Wnt family, is impaired. In contrast, the ectopic expression of porc stimulates the N-glycosylation of both endogenously and exogenously expressed Wg.