The Role of Gluten in the Development of Autoimmune Thyroid Diseases: A Narrative Review.

Context: In recent decades, adverse reactions to gluten have increased, collectively known as gluten-related disorders (GRDs). The most prominent GRD is celiac disease (CD), a T-cell-mediated autoimmune-like disorder of the small intestine triggered by the ingestion of gluten proteins in genetically predisposed individuals. Celiac disease is often associated with various autoimmune and idiopathic conditions, including autoimmune thyroid disorders (AITDs).

Emerging microfluidic technologies for CRISPR-based diagnostics: an overview.

In recent years, CRISPR (clustered regularly interspaced short palindromic repeats) has emerged as a detection technique with high specificity and sensitivity. However, it still needs improvements in terms of reducing cost, complexity, cross-contamination, technical requirements, and lack of quantification platforms. Microfluidic strategies can advance CRISPR-based technology and be modified to a higher level in the future.