Evaluating Risk Factors for Developing Hypoglycemia During Treatment of Hyperkalemia With Intravenous Regular Insulin.

The conventional dose of 10 units of intravenous (IV) regular insulin to treat hyperkalemia has been associated with hypoglycemia. There have been retrospective studies evaluating weight-based dose vs conventional dose of IV regular insulin but the comparative efficacy and safety is not well established. : Evaluate the difference in weight-based dosing of IV regular insulin between patients who experienced hypoglycemia vs.

Perceived versus actual sedation practices in adult intensive care unit patients receiving mechanical ventilation.

Background: With drug shortages, newer sedative medications, and updates in research, management of sedation and delirium in patients receiving mechanical ventilation continues to evolve.

Objective: To compare perceived and actual sedation practices for adults receiving mechanical ventilation in intensive care units (ICUs).

Methods: This was a multicenter, 2-part study conducted in adult ICUs in US hospitals.

Nephrogenic diabetes insipidus induced by two amphotericin B liposomal formulations.

Immunocompromised patients are at risk for invasive molds and resistant fungal infections for which amphotericin B may be the only feasible treatment. Nephrogenic diabetes insipidus (DI) and renal tubular acidosis are known adverse effects of conventional amphotericin B; however, nephrogenic DI has been uncommonly associated with liposomal amphotericin B formulations. We describe an 18-year-old woman with aplastic anemia who developed invasive aspergillosis.