Introduction: In commercial spaceflight, anxiety could become mission-impacting, causing negative experiences or endangering the flight itself. We studied layperson response to four varied-length training programs (ranging from 1 h-2 d of preparation) prior to centrifuge simulation of launch and re-entry acceleration profiles expected during suborbital spaceflight. We examined subject task execution, evaluating performance in high-stress conditions.
View Article and Find Full Text PDFBackground: The purpose of the present study was to develop an objective outcome measure to assess the performance of head-down bed rest subjects. The rationale behind the development was that the current outcome measure is subjective and dependent upon how much the clinical psychologist knows about subject behaviors during the study to rate them accurately.
Methods: The behaviorally anchored rating scales (BARS) were developed through the use of the critical incident technique, along with traditional BARS development procedures, and the use of focus groups.
Introduction: This report is one of a series on the Flight Analog Project, which is designed to lay the groundwork for a standard bed rest protocol. The Spaceflight Cognitive Assessment Tool for Windows (WinSCAT) is a self-administered battery of tests used on the International Space Station for evaluating cognitive functioning. Here, WinSCAT was used to assess cognitive functioning during extended head-down bed rest.
View Article and Find Full Text PDFAviat Space Environ Med
May 2009
Introduction: This report is one of a series on the Flight Analogs Project, which is designed to lay the groundwork for a standard bed rest protocol. Behavioral health services, similar to those offered to the U.S.
View Article and Find Full Text PDFThe Space Flight Cognitive Assessment Tool for Windows (WinSCAT) is used on the International Space Station to evaluate cognitive functioning after physical insult or trauma. The current study uses WinSCAT to assess cognitive functioning in a space flight analog (bed rest) environment where intermittent artificial gravity (AG) is being tested as a countermeasure. Fifteen male subjects (8 treatment, 7 control), who participated in 21 days of 6 degree head-down tilt bed rest, were assessed during the acclimatization phase, bed rest phase, and recovery phase.
View Article and Find Full Text PDFBackground: The University of California, San Francisco (UCSF) Family Alcoholism Study is a project designed to identify genetic loci that influence susceptibility to alcohol dependence and related phenotypes. Evidence supports a substantial genetic contribution to alcoholism susceptibility. However, the genetic epidemiology of alcoholism is complex, and its clinical manifestation is heterogeneous, making phenotype definition and demonstration of linkage difficult.
View Article and Find Full Text PDFAlcohol Clin Exp Res
January 2004
Background: Recruiting a large number of participants meeting strict inclusion criteria can be challenging, particularly when selecting for a condition associated with a social stigma such as alcoholism, when participation involves collection of medical specimens and sensitive information, and when the participation of family members or other collaterals is required. Developing and implementing a successful recruitment plan depends upon identifying the most effective recruitment strategies given the available resources.
Methods: Several strategies for recruiting subjects for a large family study on the genetics of alcoholism were evaluated over a two-year period with regard to participant yield, time and cost expenditure.