Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol.

Little is known about the influence of prenatal diethylstilbestrol (DES) exposure on time to pregnancy or secondary sex ratio in men. The authors evaluated these associations among men participating in the DES Combined Cohort Follow-up Study for whom exposure status was confirmed by medical record. In 2001, men provided data on their reproductive histories.

Reproductive outcomes in men with prenatal exposure to diethylstilbestrol.

Objective: To examine prenatal diethylstilbestrol (DES) exposure in relation to male reproductive outcomes.

Design: Prospective observational study.

Setting: Participants were identified through record review, clinical trial participation, or an obstetrics clinic.