JBJS Case Connect
January 2015
Case: A thirty-one-year-old woman presented with symptoms of worsening left knee and thigh pain. Radiographs and magnetic resonance imaging demonstrated extensive lytic and cystic changes throughout the femur. A biopsy demonstrated necrosis, chronic granulomatous inflammation, and laminations suggestive of an echinococcal cyst.
View Article and Find Full Text PDFAm J Orthop (Belle Mead NJ)
May 2010
Segmental neurofibromatosis (NF-5) is an extremely rare variant of neurofibromatosis involving a single extremity without pathologic features beyond the midline. A case of segmental neurofibromatosis involving the sciatic nerve and its branches is presented with a detailed description of the patient's preoperative findings plus postoperative course through 1-year follow-up. Clinical, histologic, and genetic findings are given along with a brief review of the literature on segmental neurofibromatosis.
View Article and Find Full Text PDFPrimary bone diffuse large B-cell lymphomas (PB-DLBCL) are uncommon extranodal lymphomas. Herein, we report the clinical, pathologic, immunohistochemical, and molecular features of 21 cases of PB-DLBCL. The mean age of the patients was 54 years (range: 13 to 85 y).
View Article and Find Full Text PDFPrimary bone lymphoma is an uncommon malignancy that accounts for less than 5% of all primary bone tumors. The radiographic appearances of primary bone lymphoma are variable, and, because the lesion can appear near normal on plain radiographs, a second modality such as bone scintigraphy or magnetic resonance (MR) imaging should be used. Despite this variability, the presence of a solitary, permeative, metadiaphyseal lesion with a layered periosteal reaction on plain radiographs and a soft-tissue mass on MR images, especially in a patient older than 30 years, is highly suggestive of lymphoma.
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