An HPV 16, 18, and 45 genotyping test based on Hybrid Capture technology.

Background: It has been shown that women positive for HPV 16 and HPV 18 have an increased risk of high-grade cervical intraepithelial neoplasia (CIN) compared with women positive for other high-risk (HR) HPV types. In addition, HPV 18 and HPV 45 have been closely linked to aggressive and difficult to detect adenocarcinomas.

Objectives: To develop a test based on the Hybrid Capture technology capable of specifically detecting the most important carcinogenic HPV types; 16, 18, and 45.

Sequence analysis of the msp4 gene of Anaplasma ovis strains.

Anaplasma ovis (Rickettsiales: Anaplasmataceae) is a tick-borne pathogen of sheep, goats and wild ruminants. The genetic diversity of A. ovis strains has not been well characterized due to the lack of sequence information.