Publications by authors named "Kimberly K Amrami"

Background: The articular origin of intraneural ganglion cysts has been previously described and well supported, except for the median nerve at the level of the elbow.

Observations: The authors present a patient with a median intraneural ganglion cyst at the elbow region and magnetic resonance imaging (MRI) evidence of a joint connection to the proximal radioulnar joint. A 63-year-old man presented with thumb flexion weakness and dysesthesias in the thumb, index, and middle fingers.

View Article and Find Full Text PDF

Extremely severe nausea was experienced by four subjects positioned prone on a 7T scanner table with their arm extended overhead for a wrist examination and their head positioned approximately 10-20 cm above the magnet's central axis. Movement through the large static and spatial field gradients of current 7T MRI scanner magnets typically causes mild vestibular activation which is well tolerated by most individuals. However, when positioned off-axis, the head moves through regions of even larger and more rapidly changing magnetic fields which in the current study were sufficient to induce the extremely severe nausea.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aims to improve the diagnosis of non-traumatic brachial plexopathy using deep learning models applied to routine MRI scans from patients at Mayo Clinic over a 20-year period.
  • - Researchers analyzed data from 196 patients and 256 MRI series, categorizing the abnormal cases and comparing the performance of six different deep learning approaches for identifying abnormalities in the brachial plexus.
  • - The best model, using a feature merging strategy with multiple MRI sequences, achieved a high accuracy (89.5%) and AUC (92.2%), indicating strong potential for using advanced AI techniques in diagnosing this condition.
View Article and Find Full Text PDF
Article Synopsis
  • AI is transforming radiology by improving diagnosis accuracy, speeding up interpretations, and enhancing image quality through advanced algorithms.
  • There's a risk that radiologists may overlook original images, which remain critical for accurate assessments despite AI's improvements.
  • A case study highlights this issue, showing how AI's motion suppression created a misleading appearance of an osteochondral lesion in a child’s knee, emphasizing the need for radiologists to evaluate both original and AI-enhanced images.
View Article and Find Full Text PDF

Background: The articular origin of intraneural cysts has been previously described and well supported. Intraneural ganglion cysts most commonly occur in adults and in the common peroneal nerve arising from the anterior aspect of the superior tibiofibular joint (STFJ).

Observations: The authors report a pediatric patient who developed a tibial intraneural cyst arising from the posterior aspect of the STFJ within months after surgical treatment of a peroneal intraneural cyst from the anterior aspect of the same joint.

View Article and Find Full Text PDF
Article Synopsis
  • A 23-year-old woman developed a common fibular nerve (CFN) injury resulting in foot drop after a minor ankle fracture caused by inversion during a fall.
  • The injury was initially overlooked, leading to worsening symptoms and confirming severe CFN damage through EMG studies.
  • Surgical decompression of the CFN provided her with immediate relief, supporting the theory that torsional ankle injuries can lead to nerve tension and subsequent injury at the fibular neck.
View Article and Find Full Text PDF

Automatic abnormality identification of brachial plexus (BP) from normal magnetic resonance imaging to localize and identify a neurologic injury in clinical practice (MRI) is still a novel topic in brachial plexopathy. This study developed and evaluated an approach to differentiate abnormal BP with artificial intelligence (AI) over three commonly used MRI sequences, i.e.

View Article and Find Full Text PDF

Background: Diagnosis of foveal triangular fibrocartilage complex (TFCC) tears remains difficult. The purpose of this study was to evaluate whether dynamic computed tomography (CT) of the distal radioulnar joint (DRUJ) has a higher sensitivity in detecting foveal tears of the TFCC when compared with magnetic resonance imaging (MRI).

Methods: A database query identified all patients above the age of 18 years with suspected foveal TFCC injuries who underwent bilateral dynamic CT imaging of the DRUJ, static 3T MRI, and subsequent wrist arthroscopy.

View Article and Find Full Text PDF

Background: Lipomatosis of nerve (LN) is a rare disorder characterized by the massive enlargement of peripheral nerves, frequently accompanied by generalized fibroadipose proliferation and skeletal overgrowth.

Observations: The authors have been routinely following a 20-year-old male for lipomatosis of median nerve at the wrist noted shortly after birth. He had undergone resection of the lesion accompanied by sural nerve grafting at another institution.

View Article and Find Full Text PDF

Background: Intraneural cysts involving the tibial nerve in the knee region (popliteal fossa) are rare. According to the articular (synovial) theory, which posits a joint origin for this pathology, these cysts originate from either the superior tibiofibular joint (STFJ) or the tibiofemoral (knee) joint. As tibial intraneural cysts arising from the tibiofemoral joint remain poorly understood, the authors present 2 illustrative cases and a review of the world's literature on all tibial intraneural ganglion cysts in the knee region.

View Article and Find Full Text PDF
Article Synopsis
  • IN perineuriomas, first described in 1964, are rare and benign tumors of the peripheral nerve sheath that typically affect adolescents or young adults, presenting with painless weakness or sensory loss.
  • Traditional diagnosis relied on tissue biopsy showing distinctive "pseudo-onion bulb" formation, but modern MRI techniques are now allowing some patients to skip the biopsy.
  • Recent genetic research has identified common mutations that could improve diagnosis and treatment, leading to better patient counseling and potential future therapies aimed at restoring function and understanding the condition.
View Article and Find Full Text PDF

Purpose: MRI has become an essential diagnostic imaging modality for peripheral nerve pathology. Early MR imaging for peripheral nerve depended on inferred nerve involvement by visualizing downstream effects such as denervation muscular atrophy; improvements in MRI technology have made possible direct visualization of the nerves. In this paper, we share our early clinical experience with 7T for benign neurogenic tumors.

View Article and Find Full Text PDF

Peripheral nerve injury is a common sequela of lower extremity trauma. Injuries to lower extremity nerves range from contusions and stretch injuries that will often resolve without interventions to traumatic disruptions requiring surgical procedures, including neurolysis, repair or even nerve grafting. While clinical examination and tools such as electromyography will often help to localize the site of injury, imaging is a critical tool in determining the extent and degree of nerve injury in the setting of trauma.

View Article and Find Full Text PDF

Background: Many benign and malignant tissue or bony lesions have been reported as causes of extrinsic or intrinsic posterior interosseous nerve (PIN) neuropathy at the proximal forearm/elbow region. The authors describe an unusual cause of external compression of the PIN due to a ganglion cyst arising from a radial neck pseudarthrosis (a false joint).

Observations: Decompression of the PIN with the release of the arcade of Frohse was performed with resection of the radial head and the ganglion cyst.

View Article and Find Full Text PDF

Objective: Sciatic nerve injury following total hip arthroplasty (THA) predominantly affects the peroneal division of the sciatic nerve, often causing a foot drop. This can result from a focal etiology (hardware malposition, prominent screw, or postoperative hematoma) or nonfocal/traction injury. The objective of this study was to compare the clinicoradiological features and define the extent of nerve injury resulting from these two distinct mechanisms.

View Article and Find Full Text PDF

Background: Intraneural ganglion cysts involving the tibial nerve are rare. Recent evidence has supported an articular (synovial) theory to explain the joint-related origin of these cysts; however, optimal operative treatment for cysts originating from the STFJ remains poorly understood. Therefore, we present a novel strategy: addressing the joint itself without addressing the articular branch and/or the cyst.

View Article and Find Full Text PDF
Article Synopsis
  • Myofibromas are benign tumors usually found in infants and children, and while they typically appear in the head and neck, their rare occurrence involving peripheral nerves can lead to complications.
  • A case study discusses a 16-year-old male with a rapidly growing mass in his forearm that caused severe motor weakness, diagnosed as a benign myofibroma after imaging and biopsy.
  • The surgery involved removing the tumor along with a segment of the radial nerve due to significant nerve involvement, followed by reconstruction of the nerve to restore function despite the tumor's benign nature.
View Article and Find Full Text PDF

Background: Transvaginal suspension procedures often use the sacrospinous ligament (SSL), which attaches onto the ischial spine (IS). However, nerve-related sequelae (e.g.

View Article and Find Full Text PDF

Background: Perineuriomas are peripheral nerve sheath tumors that are composed of benign, localized proliferations of perineural cells and further subclassified as intraneural or extraneural (soft tissue) based on their relationship to the histological boundaries of the nerve. Multiple histological variants have been described, and herein the authors present the first known case of a pseudolipoblastic perineurioma affecting the nerve.

Observations: A 52-year-old woman presented with a 5-year history of progressive, severe left buttock pain radiating down to the top of her foot and ankle, without any associated weakness, with a large mass in her sciatic nerve noted on magnetic resonance imaging (MRI).

View Article and Find Full Text PDF

Background: Neuromuscular choristoma (NMC) is a rare peripheral nerve lesion characterized by abnormal presence of muscle within nerve. Associated desmoid-type fibromatosis (NMC-DTF) often develops. We report F-fluorodeoxyglucose positron emission tomography (FDG PET) characteristics of NMC and NMC-DTF and propose that increased FDG activity within NMCs may be associated with subclinical NMC-DTF or NMC-DTF "precursor" tissue.

View Article and Find Full Text PDF

Background: The articular (synovial) theory describes the formation of intraneural ganglion cysts through defects in the capsule of synovial joints. While the articular theory is gaining significant traction in the literature, it is not universally accepted. Therefore, the authors present a case of a plainly visible peroneal intraneural cyst, although the subtle joint connection was not identified specifically at the time of surgery, with subsequent rapid extraneural cyst recurrence.

View Article and Find Full Text PDF

Background: Macrodystrophia lipomatosa (MDL) is characterized by progressive overgrowth affecting soft tissues and bony structures and is part of lipomatous overgrowth syndromes. MDL has been associated with lipomatosis of the nerve (LN), an adipose lesion of nerve that has a pathognomonic magnetic resonance imaging (MRI) appearance as well as a mutation in the PIK3CA gene. The authors present a case of occult LN in the setting of MDL.

View Article and Find Full Text PDF

Purpose: Intraneural (IN) perineurioma is a rare benign peripheral nerve sheath tumor, typically presenting as a painless, progressive mononeuropathy in adolescents. A rare plexal variant has been described, although there are little data describing its clinicoradiologic features. Herein, we present the largest case series of plexal IN perineuriomas reported in the literature.

View Article and Find Full Text PDF

Purpose: Hybrid peripheral nerve sheath tumors (HPNST) are a newly recognized class of peripheral nerve sheath tumor, composed of at least two areas characteristic of perineurioma, schwannoma, or neurofibroma. The literature consists only of case reports and small series; therefore, we present an illustrative case and an analysis of all reported cases of HPNST with a perineurioma component in the literature.

Methods: A systematic search of the literature was performed to identify all reported cases of hybrid perineurioma-schwannoma or perineurioma-neurofibroma in the world's literature.

View Article and Find Full Text PDF