Publications by authors named "Kimberly Farrand"
Purpose: To provide current estimates of the prevalence of diagnosed dry eye disease (DED) and associated demographics among US adults aged ≥18 years.
Design: Cross-sectional, population-based survey.
Methods: Data were analyzed from 75 000 participants in the 2013 National Health and Wellness Survey to estimate prevalence/risk of diagnosed DED overall, and by age, sex, insurance, and other demographic factors.
Background: Informant-reported outcome measures, usually completed by parents, are often administered in pediatric clinical trials with the intention of collecting data to support claims in a medical product label. Recently, there has been an emphasis on limiting these measures to observable content, as recommended in the US Food and Drug Administration guidance on patient-reported outcomes. This qualitative study explores the concept of observability using the example of childhood attention deficit/hyperactivity disorder (ADHD).
View Article and Find Full Text PDFThe purpose of this study was to conduct a retrospective analysis of serum phosphate level variability in patients new to hemodialysis (HD) and to identify patient characteristics associated with this variability. The medical records of 47,742 incident HD patients attending US outpatient dialysis centers between January 1, 2006 and March 31, 2009 were analyzed. Monthly mean serum phosphate levels determined over a 6-month evaluation period (months 4-9 after HD initiation) were assigned to one of three strata: low (<1.
View Article and Find Full Text PDFArticle Synopsis
- This study aimed to evaluate whether guanfacine extended release (GXR) affects psychomotor functioning, alertness, and daytime sleepiness in young individuals with ADHD.
- Conducted on 182 subjects aged 6 to 17, the study found no significant differences in alertness or psychomotor performance between GXR and placebo groups, though some mild to moderate sedation was reported during dosage changes.
- Results indicated that GXR significantly improved ADHD symptoms without increasing daytime sleepiness, suggesting its efficacy as a treatment option.