Publications by authors named "Kimberly Coscia"

Purpose: Adrenal vascular tumors are mainly represented by adrenal cavernous hemangiomas (ACHs) and adrenal cystic lymphangiomas (ACLs). Their radiological features often overlap with malignant tumors, therefore ruling out malignancy becomes mandatory. We analyzed clinical, radiological, and histopathological data to identify specific characteristics of these tumors.

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Article Synopsis
  • Adrenal incidentalomas (AIs) and pituitary incidentalomas (PIs) are common findings due to increased imaging, with this review focusing on the prevalence of hypercortisolism in these patients.
  • The study used PubMed to analyze demographic data and diagnostic accuracy regarding hypercortisolism and found significant links between mild autonomous cortisol secretion (MACS), cardiometabolic risks, and higher mortality.
  • Early detection and management of hypercortisolism are crucial to prevent complications, highlighting the need for targeted screening in high-risk individuals.
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Background: Various glucocorticoid replacement therapies (GRTs) are available for adrenal insufficiency (AI). However, their effectiveness in restoring glucocorticoid rhythm and exposure lacks adequate biochemical markers. We described the diurnal salivary cortisol (SalF) and cortisone (SalE) rhythm among different GRTs and analysed the associations between saliva-derived parameters and life quality questionnaires.

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Objective: Mild autonomous cortisol secretion (MACS) has been associated with a higher prevalence of osteoporosis, although most data rely on single-center studies with limited sample size. We aimed to assess the prevalence of fragility fractures and contributing factors in a large cohort of patients with adrenal incidentalomas.

Design And Methods: Medical records of 1023 patients with adrenal incidentalomas from 1990 to 2019 were reviewed, and 735 patients were selected.

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