Publications by authors named "Kimberly Chappell"

Article Synopsis
  • - The study evaluated the efficacy and safety of lotilaner (Credelio™ CAT) for flea control in cats, finding that it provided a significantly higher flea kill rate compared to fipronil + S-methoprene over a 90-day duration.
  • - A total of 343 cats across 11 veterinary clinics participated, with treatments administered on days 0, 30, and 60, and flea counts measured at multiple intervals.
  • - Results revealed that 98.3% of lotilaner-treated cats were flea-free by day 90, while only 28.8% of those on the fipronil + S-methoprene treatment were flea-free, indicating lotilaner's superior
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Article Synopsis
  • A study tested a new flea and tick treatment for dogs, lotilaner (Credelio™), showing it provided rapid and sustained knockdown of fleas for at least three months.
  • The trial involved 111 dogs receiving lotilaner and 50 receiving afoxolaner (Nexgard®), with significant reductions in flea counts seen within a month for both treatments.
  • Lotilaner had a 100% flea-free rate by Day 90, while both treatments were well-accepted by dogs and effectively managed symptoms of flea allergy dermatitis.
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Eleven laboratories collaborated to determine the periodic prevalence of in a population of dogs and cats in the United States visiting veterinary clinics. Fecal samples (2,965) solicited from 11 geographically dispersed veterinary testing laboratories were collected in 36 states between January 2012 and April 2014 and tested using a harmonized method. The overall study prevalence of in cats (3 of 542) was <1%.

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Veterinary schools are increasingly developing students' communication skills, with an emphasis placed on practice conveying medical and scientific knowledge to different audiences. We describe how patient-centered written communication has been integrated into the training of veterinary students using toxicology-related preventive materials. Third-year veterinary students were given an assignment to prepare a client-focused brochure related to veterinary toxicology.

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Three major PITX2 isoforms are differentially expressed in human, mice, zebrafish, chick, and frog tissues. To demonstrate differential regulation of gene expression by these isoforms we used three different promoters and three cell lines. Transient transfection of Chinese hamster ovary, HeLa, and LS-8 cell lines revealed differences in PITX2A and PITX2C activation of the PLOD1 and Dlx2 promoters, however, PITX2B is inactive.

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