Treatment Considerations for Unique Patient Populations With HCV Genotype 1 Infection.

Objective: To review the literature for the treatment of hepatitis C virus (HCV) genotype 1 in certain populations of patients that require further considerations before therapy initiation.

Data Sources: A systematic electronic literature search using the MEDLINE database was performed using the search terms hepatitis C, chronic hepatitis C, drug therapy, end stage liver disease, liver transplantation, HIV, hepatitis B, African Americans, renal insufficiency, obesity, pregnancy, and pediatrics.

Study Selection And Data Extraction: English language studies from January 1985 to March 2015 were considered.