Publications by authors named "Kimberly A Rzomp"
Chlamydiae are intracellular bacteria that develop within a membrane-bound vacuole called an inclusion. To ensure that the inclusion is a safe niche for chlamydial replication, chlamydiae exploit a number of host cell processes, including membrane-trafficking pathways. Recently, several Rab GTPases were found to associate with the inclusions of various chlamydial species.
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- Chlamydiae, a type of bacteria, invade host cells and create a specialized structure (inclusion) where they replicate, but the exact proteins involved in its trafficking are not fully understood.
- Researchers used green fluorescent protein (GFP) to track various Rab GTPases, which are crucial for membrane trafficking, and found that certain Rab proteins were recruited to Chlamydia infections while others were not.
- The association of Rab GTPases with the inclusion suggests a specific interaction crucial for regulating the inclusion’s trafficking and fusion with host cell membranes, even when typical cellular structures are disrupted.
Using two polymorphic genetic markers, the merozoite surface protein-3alpha (MSP-3alpha) and the circumsporozoite protein (CSP), we investigated the population diversity of Plasmodium vivax in Mae Sod, Thailand from April 2000 through June 2001. Genotyping the parasites isolated from 90 malaria patients attending two local clinics for the dimorphic CSP gene revealed that the majority of the parasites (77%) were the VK210 type. Genotyping the MSP3-alpha gene indicated that P.
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