Publications by authors named "Kimberly A Alley"
Article Synopsis
- Aminoindanol-derived bis(oxazoline) ligands are important for metal-catalyzed reactions but are difficult to modify structurally.
- Researchers developed a seven-step, large-scale synthesis of five bromine-functionalized inda(box) ligands with different substituents.
- The ligands can be further modified using Pd-catalyzed reactions, allowing for the creation of twelve new inda(box) ligands, potentially leading to new asymmetric metal-catalyzed transformations.
Article Synopsis
- This study presents a simple method for creating -disubstituted cyclooctanoids, which are important in various biologically active compounds.
- It involves using substituted 1-alkenyl-5-pentyn-1-ols with specific -dialkyl groups at certain positions to produce cyclooct-4-enone derivatives through a microwave-assisted reaction.
- The research highlights that the presence of -dialkyl groups is crucial for the reaction to work, and it also examines how to adapt the method for more complex carbocycles using a -dialkoxy system.
