General practitioner consultations for respiratory tract infections in children under 5 years; retrospective cohort study 2016-2023.

Background: Little is known about how GP consultation rates for children's respiratory tract infections (RTIs) have changed since the covid-19 pandemic restrictions lifted.

Aim: To describe changes in GP consultation rates for RTIs in children <5 years from 2016-2023.

Design And Setting: Population-based retrospective cohort study using electronic health records.

Developing a core outcome set for physical activity interventions in primary schools: a modified-Delphi study.

Objectives: To develop a core outcome set (COS) for physical activity interventions in primary schools.

Design: Modified-Delphi study.

Setting: The UK and international.

Impact of COVID-19 on outpatient appointments in children and young people in England: an observational study.

Objectives: To describe the impact of the COVID-19 pandemic on outpatient appointments for children and young people.

Setting: All National Health Service (public) hospitals in England.

Participants: All people in England aged <25 years.

Impact of COVID-19 on primary care contacts with children and young people in England: longitudinal trends study 2015-2020.

Background: The NHS response to COVID-19 altered provision and access to primary care.

Aim: To examine the impact of COVID-19 on GP contacts with children and young people (CYP) in England.

Design And Setting: A longitudinal trends analysis was undertaken using electronic health records from the Clinical Practice Research Datalink (CPRD) Aurum database.

Access to and use of contraceptive care during the first COVID-19 lockdown in the UK: a web-based survey.

Background: The first wave of lockdown measures to control the COVID-19 pandemic in the UK resulted in suspension of 'non-essential' services, including contraceptive care.

Aim: To examine women's perceptions and experiences of contraceptive care in the UK during the first lockdown.

Design & Setting: A cross-sectional survey during the lockdown period from March-June 2020.

Massive Open Online Course Evaluation Methods: Systematic Review.

Background: Massive open online courses (MOOCs) have the potential to make a broader educational impact because many learners undertake these courses. Despite their reach, there is a lack of knowledge about which methods are used for evaluating these courses.

Objective: The aim of this review was to identify current MOOC evaluation methods to inform future study designs.

Protocol for developing a core outcome set for evaluating school-based physical activity interventions in primary schools.

Introduction: Primary school-based physical activity interventions, such as The Daily Mile initiative, have the potential to increase children's physical activity levels over time, which is associated with a variety of health benefits. Comparing interventions or combining results of several studies of a single intervention is challenging because previous studies have examined different outcomes or used different measures that are not feasible or relevant for researchers in school settings. The development and implementation of a core outcome set (COS) for primary school-based physical activity interventions would ensure outcomes important to those involved in implementing and evaluating interventions are standardised.

Impact of integrating pharmacists into primary care teams on health systems indicators: a systematic review.

Background: Evidence suggests that pharmacists integrated into primary care can improve patient outcomes and satisfaction, but their impact on healthcare systems is unclear.

Aim: To identify the key impacts of pharmacists' integration into primary care on health system indicators, such as healthcare utilisation and costs.

Design And Setting: A systematic review of literature.

Examining Cost Measurements in Production and Delivery of Three Case Studies Using E-Learning for Applied Health Sciences: Cross-Case Synthesis.

Background: The World Health Report (2006) by the World Health Organization conveys that a significant increase is needed in global health care resourcing to meet the current and future demand for health professionals. Electronic learning (e-Learning) presents a possible opportunity to change and optimize training by providing a scalable means for instruction, thus reducing the costs for training health professionals and providing patient education. Research literature often suggests that a benefit of e-Learning is its cost-effectiveness compared with face-to-face instruction, yet there is limited evidence with respect to the comparison of design and production costs with other forms of instruction or the establishment of standards pertaining to budgeting for these costs.

Tools for the Diagnosis of Herpes Simplex Virus 1/2: Systematic Review of Studies Published Between 2012 and 2018.

Background: Herpes simplex virus (HSV)-1 and HSV-2 are common infections affecting the global population, with HSV-1 estimated to affect 67% of the global population. HSV can have rare but severe manifestations, such as encephalitis and neonatal herpes, necessitating the use of reliable and accurate diagnostic tools for the detection of the viruses. Currently used HSV diagnostic tools require highly specialized skills and availability of a laboratory setting but may lack sensitivity.

Massive Open Online Courses (MOOC) Evaluation Methods: Protocol for a Systematic Review.

Background: Massive open online courses (MOOCs) have increased in popularity in recent years. They target a wide variety of learners and use novel teaching approaches, yet often exhibit low completion rates (10%). It is important to evaluate MOOCs to determine their impact and effectiveness, but little is known at this point about the methodologies that should be used for evaluation.

Blockchain Implementation in Health Care: Protocol for a Systematic Review.

Background: A blockchain is a digitized, decentralized, distributed public ledger that acts as a shared and synchronized database that records cryptocurrency transactions. Despite the shift toward digital platforms enabled by electronic medical records, demonstrating a will to reform the health care sector, health systems face issues including security, interoperability, data fragmentation, timely access to patient data, and silos. The application of health care blockchains could enable data interoperability, enhancement of precision medicine, and reduction in prescription frauds through implementing novel methods in access and patient consent.

The Internet of Things in Health Care in Oxford: Protocol for Proof-of-Concept Projects.

Background: Demands on health services across are increasing because of the combined challenges of an expanding and aging population, alongside complex comorbidities that transcend the classical boundaries of modern health care. Continuing to provide and coordinate care in the current manner is not a viable route to sustain the improvements in health outcomes observed in recent history. To ensure that there continues to be improvement in patient care, prevention of disease, and reduced burden on health systems, it is essential that we adapt our models of delivery.

Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin.

Thrombus formation leading to vaso-occlusive events is a major cause of death, and involves complex interactions between coagulation, fibrinolytic and innate immune systems. Leukocyte recruitment is a key step, mediated partly by chemotactic complement activation factors C3a and C5a. However, mechanisms mediating C3a/C5a generation during thrombosis have not been studied.

What Aspects of Personal Care Are Most Important to Patients Undergoing Radiation Therapy for Prostate Cancer?

Purpose/objective: The overall quality of patient care is a function of the quality of both its technical and its nontechnical components. The purpose of this study was to identify the elements of nontechnical (personal) care that are most important to patients undergoing radiation therapy for prostate cancer.

Methods And Materials: We reviewed the literature and interviewed patients and health professionals to identify elements of personal care pertinent to patients undergoing radiation therapy for prostate cancer.

Development of indicators of the quality of radiotherapy for localized prostate cancer.

Purpose: To develop a set of indicators of the quality of radiotherapy (RT) for localized prostate cancer.

Methods And Materials: Following a comprehensive review of the literature to identify candidate quality indicators, we utilized a modified Delphi technique to develop a set of indicators of the quality of RT for localized prostate cancer. The first Delphi round consisted of an online survey in which radiation oncologists were asked to rate the importance of the candidate quality indicators.

A knowledge translation challenge: clinical use of quality of life data from cancer clinical trials.

Purpose: Measurement and reporting of health-related quality of life (HRQL) data have evolved considerably over the past 10 years. Our goal was to identify the current barriers to, and enablers of, the effective translation of HRQL outcome data from randomized clinical trials by investigating physician attitudes, knowledge, and education needs.

Methods: We undertook a mixed qualitative and quantitative study of 33 oncologists' attitudes and educational needs around the value, interpretation, and application of HRQL data from cancer clinical trials.