Publications by authors named "Kimata M"

The spin pumping effect in antiferromagnets, which ultimately converts THz waves into a spin current, is the key physical mechanism leading to an essential function which harnesses the THz technology and spintronics. Here, we report thorough experimental investigations of the spin current induced by the antiferromagnetic spin pumping effect in epitaxial α-Fe_{2}O_{3} thin films having two distinct dynamic modes and unambiguously show that both the inter- and intrasublattice spin mixing conductance are equally substantial. Our experimental insight is an important advance for understanding the physics of transduction between the spin current and the staggered magnetization dynamics at THz frequency.

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Background: Acute cholecystitis (AC) is an acute inflammatory disease of the gallbladder and one of the most frequent causes of acute abdominal pain. Early cholecystectomy is recommended for mild cholecystitis. However, the optimal surgical timing for moderate-to-severe cholecystitis requiring percutaneous transhepatic gallbladder drainage (PTGBD) remains unclear.

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Tazobactam/ceftolozane (TAZ/CTLZ) and relebactam/imipenem/cilastatin (REL/IPM/CS) are expected to be effective for treating patients with antimicrobial-resistant infections, particularly gram-negative pathogens, but nationwide surveillance of these has not been investigated thoroughly in Japan. Pseudomonas aeruginosa (n=164), Klebsiella pneumoniae (n=141), and Haemophilus influenzae (n=156) isolated from respiratory infected patients in Japan from June 2019 through December 2020 provided by the Japanese Surveillance Committee were used. Antimicrobial susceptibility testing for TAZ/CTLZ, REL/IPM and comparator agents against isolates were carried out by broth microdilution methods according to the Clinical and Laboratory Standards Institute standard.

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Article Synopsis
  • Hospital-acquired pneumonia (HAP) remains a serious and common infection in hospitals, particularly in older patient populations in Japan, with a 22% mortality rate upon discharge.
  • A retrospective study analyzed 2968 patients with HAP, using data from April 1, 2015, to May 31, 2018, revealing that most affected individuals were male and over 65 years old.
  • The study identified prevalent antibiotics prescribed, with sulbactam-ampicillin, tazobactam-piperacillin, and ceftriaxone being the most common, highlighting treatment patterns and the importance of antibiotic management in HAP cases.
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Locally advanced colon cancer (LACC) can be cured under an appropriate treatment strategy, but the decision on the treatment strategy is also important in terms of long-term prognosis. In cases with extensive abdominal wall involvement, it is especially important to secure adequate margins and repair abdominal wall defects. Recently, neoadjuvant chemotherapy (NAC) for LACC has shown promise in improving the chance of cure with tumor shrinkage.

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The mixed-valence compound YbB displays paradoxical quantum oscillations in electrical resistivity and magnetic torque in a regime with a well-developed insulating charge gap and in the absence of an electronic Fermi surface. However, signatures of such unusual fermionic quasiparticles in other bulk thermodynamic observables have been missing. Here we report the observation of a series of sharp double-peak features in the specific heat as a function of the magnetic field.

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Purpose: This Phase III, multicenter, open-label, single-arm study evaluated the safety and immunogenicity of the measles-mumps-rubella (MMR) combined vaccine, JVC-001, as a second MMR vaccination.

Methods: Healthy Japanese children aged 5-6 years received a single dose of JVC-001 following a first measles, mumps, and rubella vaccination (measles-rubella bivalent and mumps monovalent vaccine [Hoshino or Torii strain] or JVC-001) or the MMR vaccine received between ages 1 to <4 years. Immunogenicity was evaluated using antibody titers before and after vaccination (Day 1/Day 43).

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We performed a plateau-linear reaction norm model (RNM) analysis of number born alive (NBA) in purebred Landrace pigs, where breeding value changes according to maximum temperature at mating day, using public meteorological observation data in Japan. We analysed 52,668 NBA records obtained from 10,320 Landrace sows. Pedigree data contained 99,201 animals.

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  • Median arcuate ligament syndrome happens when an important artery in the stomach is squished, which can make people feel really sick.
  • A study looked at 10 patients who had surgery to fix this problem and found that their tummy symptoms got better over six months, even if the artery didn't change much.
  • Overall, the surgery helped most patients feel less pain and discomfort in their upper stomach, but not much changed for their lower stomach symptoms.
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Coronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19.

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Polar metals have recently garnered increasing interest because of their promising functionalities. Here we report the experimental realization of an intrinsic coexisting ferromagnetism, polar distortion and metallicity in quasi-two-dimensional CaCoO. This material crystallizes with alternating stacking of oxygen tetrahedral CoO monolayers and octahedral CoO bilayers.

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Rationale: Although patients with central disorders of hypersomnolence (CDH) exhibit characteristic symptoms of hypersomnia frequently, it takes 5 to 15 years from the onset for its diagnosis due to the lack of symptom recognition. Here, we present a case of idiopathic hypersomnia (IH), a CDH, wherein early diagnosis was aided by a video footage of a spontaneous sleep attack.

Patient Concerns: A 21-year-old man lost consciousness while driving and experienced an accident.

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Introduction: Molnupiravir is an orally available prodrug of N-hydroxycytidine that received special approval for emergency treatment of coronavirus disease 2019 (COVID-19) in Japan in December 2021 and full approval in April 2023. To assess the real-world safety and effectiveness of molnupiravir in Japanese patients with COVID-19, we conducted nationwide post-marketing surveillance to collect data at registered institutions in Japan.

Methods: The surveillance data were collected from December 27, 2021, to May 2, 2023.

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The potential spin-triplet heavy-fermion superconductor UTe exhibits signatures of multiple distinct superconducting phases. For field aligned along the b axis, a metamagnetic transition occurs at μH ≈ 35 T. It is associated with magnetic fluctuations that may be beneficial for the field-reinforced superconductivity surviving up to H.

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A 70-year-old female patient was admitted for close examination and treatment of hypercalcemia (corrected serum calcium levels: 3.04 mmol/L) and renal dysfunction (serum creatinine levels: 254.59 µmol/L).

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An 80-year-old man presented with electrolyte abnormalities, particularly hypocalcemia (3.6 mg/dL). He was diagnosed with bone and lymph node metastases from prostate cancer seven years earlier and continuously received goserelin, bicalutamide, and zoledronate.

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Background: The prevalence of Holter-based late potentials (H-LPs) in cases of fatal cardiac events has increased. Although the noise level of H-LP is higher than that of conventional real-time late potential (LP) recording, a procedure to reduce the noise severity in H-LP by increasing the averaging beats has not been investigated.

Methods: We enrolled 104 patients with post-myocardial infarction (MI) and 86 control participants.

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: Holter-based late potentials (LPs) are useful for predicting lethal arrhythmias in organic cardiac diseases. Although Holter-based LPs exhibit diurnal variation, no studies have evaluated the optimal timing of LP measurement over 24 h for predicting lethal arrhythmia that leads to sudden cardiac death. Thus, this study aimed to validate the most effective timing for Holter-based LP testing and to explore factors influencing the diurnal variability in LP parameters.

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Objective: Persistent proatlantal artery (PPA) is a primitive carotid-vertebrobasilar anastomosis (CVA); acute ischemic stroke due to basilar artery (BA) occlusion via a PPA is extremely rare.

Case Presentation: An 84-year-old female developed disturbance of consciousness (Glasgow Coma Scale E2V1M5) and quadriparesis with a National Institutes of Health Stroke Scale score of 35. Head CT revealed early ischemic changes in the right temporal lobe, and a hyperdense vessel sign in the BA.

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The superconducting (SC) phase diagram in uranium ditelluride is explored under magnetic fields (H) along the hard magnetic b axis using a high-quality single crystal with T_{c}=2.1  K. Simultaneous electrical resistivity and ac magnetic susceptibility measurements discern low- and high-field SC (LFSC and HFSC, respectively) phases with contrasting field-angular dependence.

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Background: Endoscopic submucosal dissection (ESD) is the standard treatment for early gastric cancer in Japan. Pathological evaluation of ESD specimens is considered essential to determine if additional gastrectomy is necessary. Usually, specimens resected by ESD are sliced into 2-3 mm wide sections, and each section is examined for depth of tumor and lymphovascular invasion.

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Article Synopsis
  • Intraocular hemorrhage (bleeding inside the eye) can impact vision and may be linked to antithrombotic medications (like antiplatelets and anticoagulants), but research on this risk, particularly with combination therapies, is limited.
  • The study analyzed data from a large pharmacovigilance database to assess the occurrence of intraocular hemorrhage with various antiplatelet and anticoagulant therapies, finding specific drugs (like aspirin and warfarin) associated with these risks.
  • Notable findings include signals for intraocular hemorrhage in younger patients on aspirin monotherapy and in elderly patients on both monotherapy and combination therapy with warfarin, with a median
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Background: The advent of novel monitoring technologies has dramatically increased the use of ambulatory electrocardiography (AECG) devices. However, few studies have conducted detailed large-scale investigations on the incidence of arrhythmias over 24 h, especially ectopy, in healthy individuals over a wide age range.

Objectives: This study aimed to investigate the incidence of arrhythmias detected using AECG and associated factors, in healthy individuals, over a wide age range.

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Introduction: Molnupiravir is an oral antiviral drug that received special approval for emergency use in Japan on December 24 2021 for infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This post-marketing surveillance (PMS) is underway to investigate the safety and effectiveness of molnupiravir in daily clinical practice in Japan. The interim PMS data collected from December 27 2021 to June 15 2022 are reported in this publication.

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  • The study investigates the effects of quercetin monoglucuronides, specifically their biological activities in activated macrophages, focusing on quercetin-3-glucuronide (Q3G) and its positional isomers.
  • Q3G demonstrated the strongest ability to inhibit pro-inflammatory responses, while Q7G showed higher cytotoxicity due to its lower stability in neutral pH.
  • Findings indicate that the effectiveness of these quercetin derivatives may be influenced by their stability and ability to convert back to quercetin aglycone, which plays a role in their biological functions.
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