Publications by authors named "Kim-Chi Thi Vu"
Article Synopsis
- Flavivirus infections, such as Zika and West Nile, significantly impact the host's lipid metabolism, leading to changes in specific lipid levels early in the infection.
- Increased levels of certain lipids, like ceramides, and alterations in glycerophospholipid and fatty acid metabolism are observed, especially in viruses causing cell damage.
- Disrupting specific lipid-related enzymes can reduce virus replication and effects on cells, indicating that lipid remodeling is crucial for the infection and replication of orthoflaviviruses.
Function of , a homolog, in appressorium formation and cAMP signal transduction in .
Biosci Biotechnol Biochem
November 2020
A novel homolog of , a global regulatory gene in filamentous fungi, was identified from . A deletion mutant of the homolog () exhibited lowered intracellular cAMP levels, and decreased appressorium formation on non-host surface; the decrease was recovered using exogenous cAMP and IBMX, indicating that deletion affected the cAMP signaling pathway.
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- The study aimed to investigate the natural bacterial hosts of antimicrobial resistance genes (ARGs) and understand their evolutionary dynamics and spread.* -
- Carbapenem-resistant Shewanella xiamenensis strains from Vietnamese water sources were genetically sequenced, revealing the presence of conserved bla-like carbapenemase genes in their genomes.* -
- Findings suggest that S. xiamenensis may serve as a significant natural reservoir for ARGs, shedding light on the environmental evolution and dissemination of these resistance genes in Vietnam.*