Cortisol is negatively associated with insulin sensitivity in overweight Latino youth.

Context And Objective: The purpose of the present study was to investigate the cross-sectional and longitudinal associations of serum morning cortisol and aspects of insulin action in Latino children and adolescents (8-13 yr) at risk for type 2 diabetes.

Design And Participants: The present study includes a cross-sectional analysis in 211 participants and a longitudinal analysis in a subset of 143 participants.

Results: At baseline, cortisol was negatively associated with fasting glucose (r = 0.