Publications by authors named "Kim N Zeiner"
Article Synopsis
- - The S2k guideline on venous leg ulcers was developed by a collaborative group led by the German Society of Phlebology and Lymphology, including various other German medical societies.
- - The goal is to unify different medical approaches to create a comprehensive treatment framework for venous leg ulcers, benefiting both patients and healthcare professionals.
- - It includes 70 specific recommendations across key areas like diagnostics, therapy, prevention of recurrences, and everyday challenges, reflecting the latest scientific knowledge for clinical practice.
Article Synopsis
- In cancer treatment, "lines of therapy" (LOT) is a term that means different things to different doctors, and they don't all agree on its definition.
- A study in Germany found that doctors often have trouble understanding LOT and have had misunderstandings with their colleagues about it.
- Experts discussed various factors that affect LOT, like types of treatments and therapy breaks, but they mostly agreed on what should matter when deciding about LOT.
Objective: In rheumatoid arthritis (RA), chronic inflammation can enhance the development of sarcopenia with a depletion of muscle mass, strength and performance. Currently, a consensus definition for sarcopenia and solid results for the prevalence of sarcopenia in patients with RA are lacking.
Methods: In this cross-sectional study, 289 patients ≥18 years with RA were recruited.
Background: Postural control is associated with fall risk. Patients with rheumatoid arthritis (RA) have a higher risk to fall than healthy subjects. The objective of this study was to identify associations between variables of postural control with prospective falls in patients with RA.
View Article and Find Full Text PDFBackground: Patients with rheumatoid arthritis (RA) are at increased risk of falls and fractures. Sarcopenia occurs more frequently in RA patients due to the inflammatory processes. Early diagnosis and prevention programmes are essential to avoid serious complications.
View Article and Find Full Text PDFBackground: Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking.
Methods: A novel approach of reference-free deconvolution of large-scale DNA methylation data enabled us to develop a machine learning classifier based on CpG sites, specific for latent methylation components (LMC), that allowed for patient allocation to prognostic clusters.
Background: An experienced life-threating anaphylactic reaction to hymenoptera venom can sustainably impair patients' quality of life (QoL). Besides carrying emergency medication, venom-specific immunotherapy (VIT) exists as a causal treatment of allergy.
Objective: This study aimed to examine QoL, anxiety, depression, and physical and mental health in patients allergic to hymenoptera venom before and during VIT and the impact of a tolerated sting challenge (SC).
Article Synopsis
- A study investigated the characteristics of patients diagnosed with both hidradenitis suppurativa (HS) and plaque psoriasis (Pso), highlighting the onset age, disease severity, and treatment approaches.
- Of the 28 patients evaluated, those diagnosed with HS first experienced a more severe form of the disease compared to those diagnosed with Pso first, with an average onset time for the second disease being approximately 14 years later.
- The most common comorbidities were obesity, psychiatric issues, and psoriatic arthritis, with adalimumab identified as the most effective treatment for both conditions.