A Perilous Combination: Coinfection with Human Plague-Report of Two Cases and Review of the Literature, 1937-2022.

Plague in humans and animals is caused by , a zoonotic gram-negative bacterium endemic in certain regions of Asia, Africa, and the United States. Coinfection with both and Streptococci species has been anecdotally reported in humans and associated with severe and rapidly fatal disease. This report presents two cases of patients who died following and coinfection.