Publications by authors named "Kim J R Blezer"
Article Synopsis
- Capsids of the cowpea chlorotic mottle virus (CCMV) show potential as therapeutic nanocarriers, but their instability at physiological pH has limited cargo incorporation methods.
- Researchers developed a method using a stabilized variant of the CCMV coat protein, co-expressing it with proteins like mEGFP in E. coli for effective cargo loading.
- The results demonstrated that the co-expression process does not harm E. coli cells and ensures proper folding of the mEGFP, making this strategy viable for producing cargo-loaded CCMV nanoparticles.
