Kidney Replacement Therapies and Outcomes in Children With Crush Syndrome-Associated Kidney Injury.

Importance: This study addresses the characteristics, kidney replacement therapy (KRT) modalities, and outcomes in children diagnosed with crush syndrome following an earthquake in Turkey.

Objective: To analyze the associations of different KRT modalities with long-term dialysis dependency and length of stay (LOS) in the pediatric intensive care unit (PICU).

Design, Setting, And Participants: This multicenter, prospective, and retrospective cohort study was conducted across 20 PICUs in Turkey.

Major advances in protein function assignment by remote homolog detection with protein language models - A review.

There is an ever-increasing need for accurate and efficient methods to identify protein homologs. Traditionally, sequence similarity-based methods have dominated protein homolog identification for function identification, but these struggle when the sequence identity between the pairs is low. Recently, transformer architecture-based deep learning methods have achieved breakthrough performances in many fields.

An Assessment of Intermittent and Continuous Enteral Feeding in Critically Ill Children.

Background: The inability to ensure adequate nutrition for patients, and failure to provide adequate calorie and protein intake, result in malnutrition, leading to increased morbidity and mortality. The present study assesses the two approaches to enteral nutrition-intermittent and continuous enteral feeding-in critically ill pediatric patients in Türkiye to determine the superiority of one method over the other.

Methods: Included in this multicenter prospective study were patients receiving enteral nutrition via a tube who were followed up over a 3-month period.

Exploring performance profiles of home health care agencies: A two-stage analytical approach.

Background: Public reporting of home health care agencies' performance metrics, including patient satisfaction, care processes, and health outcomes, aims to inform customer decisions and encourage agencies to improve the quality of services. However, there is limited research that examines the heterogeneous performance of home health care agencies.

Purposes: The aim of this study was to analyze the performance of home health care agencies by identifying distinct subgroups of agencies with similar performance profiles and describing the relationships between agency characteristics and such subgroups.

Severe pertussis infections in pediatric intensive care units: a multicenter study.

Unlabelled: This study aims to evaluate the clinical course of critical pertussis illness to the pediatric intensive care unit in Istanbul. The study was conducted as a multicenter, retrospective study between January 1, 2023, and December 31, 2023. Cases with positive polymerase chain reaction testing for Bordetella pertussis of nasopharyngeal swab samples within the first 24 h of pediatric intensive care unit admission were recorded.

Comparison of AI applications and anesthesiologist's anesthesia method choices.

Background: In medicine, Artificial intelligence has begun to be utilized in nearly every domain, from medical devices to the interpretation of imaging studies. There is still a need for more experience and more studies related to the comprehensive use of AI in medicine. The aim of the present study is to evaluate the ability of AI to make decisions regarding anesthesia methods and to compare the most popular AI programs from this perspective.

Impact of obesity on subarachnoid hemorrhage-induced cerebral vasospasm: An experimental rat model.

Aim: Obesity has emerged as a critical risk factor for various cerebrovascular diseases. Studies have demonstrated the detrimental effects of obesity on vascular health, including endothelial dysfunction, inflammation, and oxidative stress, which may exacerbate vascular complications following hemorrhagic stroke. In this study, the effect of obesity on the severity of cerebral vasospasm after subarachnoid hemorrhage was investigated.

Elevated Urotensin-II and TGF-β Levels in COPD: Biomarkers of Fibrosis and Airway Remodeling in Smokers.

Small airway fibrosis plays a critical role in the progression of chronic obstructive pulmonary disease (COPD). Previous research has suggested that Urotensin-II (U-II) and transforming growth factor-β (TGF-β) may contribute to pathological fibrosis in various organs, including the cardiovascular system, lungs, and liver. However, their specific relationship with airway fibrosis in COPD has not yet been thoroughly investigated.

Improving the Annotations of JCVI-Syn3a Proteins.

The JCVI-Syn3 organism is a minimal organism derived from Mycoplasma mycoides capri, which is capable of self-replication. While the ancestor has 863 genes, the synthetic progeny has only 473, with 434 of these coding for proteins. Despite initial efforts to understand all functions of the organism, a significant number of these protein-coding genes still have unknown functions, and subsequent studies have been only partially successful in elucidating their roles.

EFFECT OF KYPHOPLASTY ON PAIN CONTROL AND VERTEBRAL RESTORATION.

Background And Aim: Numerous studies have been conducted regarding vertebral restoration, development of kyphotic deformity, and pain control following balloon kyphoplasty. However, there is no consensus regarding the ideal time to perform kyphoplasty. Herein, we aimed to compare the results of treatment of different vertebral levels following early or late kyphoplasty.

Can Timed Up and Go Test discriminate the risk of falling in patients with Multiple Sclerosis with low to moderate impairment?

Purpose: The aim of the study was to discriminate the risk of falling in patients with Multiple Sclerosis with low to moderate impairment who do not use walking aid using the Timed Up and Go (TUG) Test.

Methods: This study was planned as a prospective descriptive study with 204 patients. Falls were recorded in three-month prospective diaries, and the balance was evaluated using the TUG Test.

Coexistence of Celiac Disease and Allergic Wheat Sensitivity: An Observational Study of Daily Clinical Practice.

Introduction: Although separate immunogenic mechanisms are involved, IgE-type sensitization to wheat and celiac disease (CD) may coexist. We observationally assessed the importance of this relationship in daily practice using CD and wheat sensitization screenings.

Methods: Celiac antibody (CA) screening and food prick tests (FPTs) were requested simultaneously from patients who presented to the Allergy Clinic between January 2022 and December 2023 and had any complaint accompanied by CD symptoms/findings (non-celiac group).

Pushing the tuning limits of femtosecond Yb-based solid-state lasers to 1 µm: a Yb:YVO laser tunable down to 1004 nm.

We have obtained what we believe to be the shortest fs tuning wavelength (1004 nm) from a Yb-based solid-state laser system. As the working horse, we have chosen Yb:YVO due to its blueshifted gain spectrum. While using a single 10 W 952 nm diode for pumping and a semiconductor saturable absorber mirror (SESAM) for mode-locking, we have achieved 266 fs long pulses with up to 1.

Vidian Canal in Chiari Type I Malformation: A Computed Tomography Study.

Objective: To evaluate the position and dimension of the Vidian canal (VC) in Chiari type I malformation (CIM).

Materials And Methods: Radiologic views of 49 CIM (mean age: 23.58±15.

Drug Allergies in Older Adults: A Major Problem in a Specific Population.

Introduction: The use of medications in older adults is increasing due to the prevalence of chronic diseases. Data on the characteristics of drug allergies (DAs) in older adults are limited. This study investigated the prevalence and clinical characteristics of DAs in patients aged 65 years and older.

Posterior clinoid process in children: morphometric analysis, pneumatization ratio, and surgical implications.

Purpose: To describe pneumatization and topographic position of the posterior clinoid process (PCP) in healthy children when approaching the anterior and middle fossae.

Methods: The study consisted of computed tomography images of 180 pediatric patients (90 males / 90 females), aged 1-18 years. The presence or absence of PCP pneumatization was noted, and the distances of certain landmarks to PCP were measured.

The clinical and immunological characteristics of common variable immunodeficiency in adults and older adults.

Objective: The aim of this study was to determine the clinical and immunological characteristics of older adults with common variable immunodeficiency (CVID).

Methods: Patients aged ≥18 years who were followed up with the diagnosis of CVID between 2015 and 2020 were included in the study. The patients were separated into two age groups according to the age at diagnosis: the adult group, aged 18-65 years (n=49) and the older adult group, aged ≥65 years (n=11).

CMUT as a Transmitter for Microbubble-Assisted Blood-Brain Barrier Opening.

Focused ultrasound (FUS) combined with microbubbles (MBs) has emerged as a promising strategy for transiently opening the blood-brain barrier (BBB) to enhance drug permeability in the brain. Current FUS systems for BBB opening use piezoelectric transducers as transmitters and receivers. While capacitive micromachined ultrasonic transducers (CMUTs) have been suggested as an FUS receiver alternative due to their broad bandwidth, their capabilities as transmitters have not been investigated.

A 1.11 mm2 IVUS SoC with ±50°-Range Plane Wave Transmit Beamforming at 40 MHz.

Intravascular ultrasound (IVUS) imaging catheters are significant tools for cardiovascular interventions, and their use can be expanded by realizing IVUS imaging guidewires and microcatheters. The miniaturization of these devices creates challenges in SNR due to the need for higher frequencies to provide adequate resolution. An integrated IVUS system with transmit beamforming can mitigate these limitations.

Dual-wavelength synchronously mode-locked Cr:LiSAF laser with a tunable beating frequency and a central wavelength.

We demonstrate a versatile dual-wavelength synchronous mode-locking of a diode-pumped Cr:LiSAF laser for the first time, to our knowledge. A two-color mode-locked operation is achieved by using intracavity birefringent filters (BRFs) or etalons as frequency-selective elements. Using filters with different thicknesses and hence different free spectral ranges (FSRs), wavelength separation in two-color mode-locking could be selected between 1 and 9 nm, with corresponding beating frequencies in the 0.

The effects of myofascial release in combined with task-oriented circuit training on balance in people with Parkinson's disease: a randomized pilot trial.

Objectives: Task-oriented circuit training (TOCT) has been used to improve balance in people with Parkinson's disease (pwPD). To investigate the effectiveness of TOCT on balance, quality of life, and disease symptoms when combined with myofascial release in pwPD.

Methods: Twenty-six pwPD were randomized into two groups for this randomized controlled study.

Radiologic evaluation of the Vidian canal in the pediatric population.

Purpose: This examination aimed to display the size and topographic position of the Vidian canal (VC) in normal children.

Methods: 180 pediatric subjects aged 1-18 years were included this computed tomography examination. The distances of VC to certain landmarks, and VC length were measured.