Publications by authors named "Kilian Zuchan"
The dyad of the Y-junction- and a flavin module unites diverse redox enzymes.
Biochim Biophys Acta Bioenerg
June 2021
Article Synopsis
- Two distinctive polypeptide modules, the "Y-junction" and the "flavin" module, are found in various enzymes like complex I and hydrogenases, indicating their functional diversity.
- The flavin module interacts with the substrate NAD(P) and facilitates electron exchange, while the Y-junction module acts as an electron transfer hub with multiple entry and exit sites.
- Research into genomes shows that these modules likely existed in the last universal common ancestor, suggesting an evolutionary link between them and the development of complex I.