Does ascorbic acid protect against vanadium neurotoxicity in different regions of rat brain?

Objective: Ascorbic acid is a powerful antioxidant and protects against lipid peroxidation in cerebral membrane. The objective of the study was to investigate protective effects of ascorbic acid on lipid peroxidative damage and perturbation of enzymes, glucose-6-phosphate dehydrogenase (G6PDH) and acetylcholinesterase (AChE) in discrete regions of rat brain after vanadium exposure.

Methods: This study was carried out at Al-Arab Medical University, Benghazi, Libya, from 1995 to 1996.