In this study, 11 species of the genus Diduga Moore, [1887] are recognized from Thailand, including a new species, Diduga siamensis Bayarsaikhan & Heppner sp. nov., and one newly recorded species, D.
View Article and Find Full Text PDFThe genus Diduga Moore, [1887] is reviewed with 11 species from Laos, including one new species, D. bantha sp. nov.
View Article and Find Full Text PDFThe Hedgehog (Hh) signaling pathway plays an essential role in the initiation and progression of prostate cancer. This is mediated by transcriptional factors belonging to the GLI (glioma-associated oncogene) family, which regulate downstream targets to drive prostate cancer progression. The activity of GLI proteins is tightly controlled by a range of mechanisms, including molecular interactions and post-translational modifications.
View Article and Find Full Text PDFThe genus Stictane Hampson is reviewed in Laos, with eight species including four newly recorded species, S. obscura (Inoue, 1976), S. pectinata Holloway, 2001, S.
View Article and Find Full Text PDFRapid environmental changes can dramatically and durably affect the animal's foraging behavior. In the Ross Sea (Antarctica), calving of the Nansen Ice Shelf in 2016 opened a newly accessible marine area of 214 km. In this study, we examined the foraging behavior of Adélie penguins from the nearby Inexpressible Island in December 2018, by tracking 27 penguins during their at-sea trips using GPS, depth and video loggers.
View Article and Find Full Text PDFTheory predicts that sympatric predators compete for food under conditions of limited resources. Competition would occur even within the same species, between neighboring populations, because of overlapping foraging habits. Thus, neighboring populations of the same species are hypothesized to face strong competition.
View Article and Find Full Text PDFAs international food trade increases, consumers are becoming increasingly interested in food safety and authenticity, which are linked to geographical origin. Adzuki beans () are cultivated worldwide, but there are no tools for accurately discriminating their geographical origin. Thus, our study aims to develop a method for discriminating the geographical origin of adzuki beans through targeted and non-targeted metabolite profiling with gas chromatography time-of-flight mass spectrometry combined with multivariate analysis.
View Article and Find Full Text PDFBluetongue is a re-emergent arthropod-transmitted viral disease that affects all wild and domestic ruminant species, reducing herd productivity. The epidemiology of bluetongue virus (BTV) infection is poorly defined in much of the world, including extensive portions of Asia and the Middle East. In the Republic of Korea (ROK), scarce information is available on the status of BTV infection.
View Article and Find Full Text PDFComput Math Methods Med
October 2018
We propose a novel method that predicts binding of G-protein coupled receptors (GPCRs) and ligands. The proposed method uses hub and cycle structures of ligands and amino acid motif sequences of GPCRs, rather than the 3D structure of a receptor or similarity of receptors or ligands. The experimental results show that these new features can be effective in predicting GPCR-ligand binding (average area under the curve [AUC] of 0.
View Article and Find Full Text PDFUnlabelled: Peppers are widely consumed in Korea; the varietal development of peppers with increased content of beneficial plant metabolites is, therefore, of considerable interest. This requires a comprehensive understanding of the metabolic profile of pepper plants and the factors affecting this profile. To this end, we determined the content of various metabolites, such as hydrophilic and lipophilic compounds, phenolic acids, carotenoids, and capsaicinoids in peppers of various colors (green, red, pale green, and violet peppers) and in a high-pungency (green) pepper.
View Article and Find Full Text PDFVarious adamantane sulfonamides showed potent inhibitory activity against 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). In continuation of our efforts to discover a more potent, selective and metabolically stable 11β-HSD1 inhibitor in mice as well as in humans, we optimized the adamantane sulfonamide using structure-based molecular modeling. Compound 3, which has alkyl side chains on the linker, demonstrated a potent inhibitory activity against human and mouse 11β-HSD1 (IC50 of 0.
View Article and Find Full Text PDFFollowing consumption of their mother, the subsocial spider Amaurobius ferox remain together, exhibiting distinctive behaviours in response to intruders into the natal nest. We examined the ontogeny and characteristics of locomotory behaviours in A. ferox during this post-maternal social period.
View Article and Find Full Text PDFConstruction of a safe refuge is the first step toward the evolution of social organization in spiders. In the case of the subsocial spider Amaurobius Jerox (Araneae, Amaurobiidae), the young remain in the natal nest after consuming their mother's body (matriphagy). The benefit that the young could obtain from the maternal web was investigated in their collective prey capture.
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