Publications by authors named "Kil Hun Lee"
Article Synopsis
- * The observational study included over 54,000 participants, with COVID-19 infection rates being slightly lower for NVX-CoV2373 at 30 days post-vaccination compared to BNT162b2 (7.9% vs. 8.6%).
- * At 60 and 90 days, infection rates increased for both vaccines, and the risk ratio suggested NVX-CoV2373 offered similar protection compared to BNT162b2, highlighting the need for ongoing
Comparative Effectiveness of COVID-19 Bivalent Versus Monovalent mRNA Vaccines in the Early Stage of Bivalent Vaccination in Korea: October 2022 to January 2023.
Ryu Kyung Kim Young June Choe Eun Jung Jang Chungman Chae Ji Hae Hwang Kil Hun Lee Jae Young Lee Sang Won Lee
J Korean Med Sci
November 2023
Article Synopsis
- This study analyzed over 2 million people in South Korea to compare the effectiveness of COVID-19 bivalent vaccines versus monovalent vaccines in preventing severe infections and deaths.
- Bivalent vaccine recipients showed much lower rates of infection, critical illness, and death compared to those who received monovalent vaccines, with effectiveness rates up to 85.3% against death shortly after vaccination.
- The findings suggest that bivalent vaccines offer significant additional protection during the omicron variant phase of the pandemic, demonstrating sustained effectiveness over time.
Article Synopsis
- The study examined deaths from COVID-19 reinfection in South Korea, focusing on risk factors during a period dominated by the omicron BA.1/BA.2 variant.
- Residents of long-term care facilities were found to have a significantly higher risk of reinfection compared to the general population, especially those unvaccinated.
- Additionally, the risk of death from reinfection was notably higher in older adults (ages 60-74) and immunocompromised individuals, suggesting the importance of vaccination to reduce reinfection and severe outcomes.*
Article Synopsis
- This study aimed to evaluate the effectiveness of bivalent versus monovalent COVID-19 vaccines during the 2022-2023 winter using real-world data from South Korea.
- The research included 29,245 adults and found that bivalent vaccine recipients had a 12.2% higher protection against COVID-19 compared to those receiving the monovalent vaccine, especially noted at 39.4% for individuals in long-term care facilities.
- The study concludes that bivalent vaccines offer superior protection, suggesting they should be prioritized in immunization programs to combat seasonal COVID-19 outbreaks.
Article Synopsis
- The Korea Disease Control and Prevention Agency analyzed the impact of its nationwide COVID-19 vaccination campaign from February 2021 to October 2022.
- The study estimated that the vaccination prevented 95,786 severe cases and 112,195 deaths, demonstrating its significance in controlling the pandemic's severity.
- If the vaccination campaign hadn't occurred, the expected cases and deaths would have been at least four times higher, highlighting its effectiveness in reducing COVID-19 severity in the Republic of Korea.
Article Synopsis
- A study in South Korea analyzed the risk of reinfection for COVID-19 among residents from January to August 2022.
- Children aged 5-11 years and 12-17 years were found to have a higher risk of reinfection, with adjusted hazard ratios of 2.20 and 2.00, respectively.
- Receiving a 3-dose COVID-19 vaccination significantly reduced the risk of reinfection, with an adjusted hazard ratio of 0.20.