Publications by authors named "Kikiana Hurwitz"
Article Synopsis
- Researchers studied jellyfish venom to identify its biomedical potential, focusing on its effects on mouse dorsal root ganglia (DRG) cells.
- They found that while crude venom caused cell death, purified venom fractions showed specific, reversible effects on different cell types, categorized into three phenotypic responses (A, B, C).
- The study highlights that jellyfish venom contains diverse compounds that can interact with ion channels and receptors, indicating possible wide-ranging physiological applications.
Species of the box jellyfish (Cubozoa) genus Alatina are notorious for their sting along the beaches of several localities of the Atlantic and Pacific. These species include Alatina alata on the Caribbean Island of Bonaire (the Netherlands), A. moseri in Hawaii, and A.
View Article and Find Full Text PDFDespite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that (1) recapitulate live-tentacle stings; (2) allow quantitation and imaging of cnidae discharge; (3) allow primary quantitation of venom toxicity; and (4) employ rigorous controls. We report the implementation of an integrated array of three experimental approaches designed to meet the above-stated criteria.
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