Publications by authors named "Kiki Juhler"
Article Synopsis
- CGRP receptor antagonists and monoclonal antibodies have emerged as new treatment options for migraines, affecting CGRP-R and AMY-R.
- Experiments showed that CGRP led to increased current in receptor-expressing oocytes, with higher potency on CGRP-R than AMY-R or calcitonin receptors.
- Both erenumab and rimegepant were found to be effective antagonists for CGRP-R and AMY-R, but with a stronger preference for CGRP-R, potentially explaining the adverse effect of constipation associated with CGRP-R antagonism.
