Associations between depression and unhealthy behaviours related to metabolic syndrome: a cross sectional study.

Background And Objectives: The purpose of the present study was to determine whether depression was associated with metabolic syndrome and unhealthy behaviours in community residents.

Methods And Study Design: Using the 2009-2010 baseline data of the Saku Cohort Study, 1,225 men and women who participated in a community health screening were included in the cross-sectional analyses. Depression was assessed using the Zung Self-Rating Depression Scale.

Low-molecular-weight adiponectin and high-molecular-weight adiponectin levels in relation to diabetes.

Objective: To evaluate the association between adiponectin complexes (high-molecular-weight [HMW], middle-molecular-weight [MMW], and low-molecular-weight [LMW] adiponectin) and diabetes.

Design And Methods: We conducted a case-control study, based on a cohort in Saku, Japan. Among 2565 participants, 300 participants with diabetes and 300 matched controls (430 men and 170 women) were analyzed.

Reduction in adiposity, β-cell function, insulin sensitivity, and cardiovascular risk factors: a prospective study among Japanese with obesity.

Background: A reduction in adiposity may be associated with an improvement in insulin sensitivity and β-cell function as well as cardiovascular disease (CVD) risk factors; however, few studies have investigated these associations in a longitudinal setting.

Methods: To investigate these associations over a 1-year period, we conducted an observational analysis of 196 Japanese subjects with obesity in the Saku Control Obesity Program. We investigated the relations between changes in adiposity (body mass index [BMI], waist circumference, subcutaneous fat area [SFAT], and visceral fat area [VFAT]) and changes in HbA1c, fasting plasma glucose (FPG), insulin sensitivity index (ISI), the homeostasis model assessment β cell function (HOMA-β), lipids, and blood pressure.