The role of capital structure management in maintaining the financial stability of hotel firms during the pandemic-A global investigation.

Due to the detrimental effects of the Covid-19 pandemic on the hotel sector, pandemic crisis management research has received lots of academic attention, from studies in sales-marketing to human resource management. However, financial management has been largely overlooked in the agenda of pandemic crisis management and hotel resilience. Therefore, this paper aims to address the research gap by exploring the role of capital structure management in maintaining financial stability and resilience capacities of hotel firms during this evolving and unpredictable Covid-19 pandemic.

Optimal Design of a Leaf Flexure Compliant Mechanism Based on 2-DOF Tuned Mass Damping Stage Analysis.

This study proposed an innovative design of a leaf flexural-based 2-DOF tuned mass damping stage that can be integrated into a micro-electromechanical system precision positioning stage to reduce the displacement response of the precision positioning stage excited by a specific vibration frequency and to achieve the damping effect and vibration reduction without adding viscous damping materials. A prototype that conforms to dual-axis decoupling and has 2-DOF translation capability was designed using parallel and vertical arrangements of a leaf flexure. The Taguchi design method and the finite element method were used on the relevant design parameters of the primary mass stage to determine the best size configuration for the maximum off-axial stiffness ratio and the parameters of the tuned mass damper closest to the natural frequency of the primary mass stage with the minimum deflection.

A novel approach to increase awareness about hereditary colon cancer using a state cancer registry.

Purpose: The aim of this project was to conduct educational outreach about hereditary colon cancer to a targeted high risk population identified through a state cancer registry.

Methods: Individuals who met one of the first three Bethesda criteria guidelines were identified through the Colorado Central Cancer Registry. The physician of record received a brochure, survey and form to provide written consent to contact patient(s).

Lack of association between sputum atypia and chronic obstructive pulmonary disease mortality.

Hypothesis: Chronic obstructive pulmonary disease (COPD) and lung cancer are thought to share common elements in pathogenesis. The authors hypothesized that sputum atypia would reflect the processes leading to progressive airflow obstruction and might be a novel biomarker of more rapidly progressive COPD.

Methods: The authors analyzed the association between COPD death and sputum cytologic atypia in an ongoing cohort of 2013 smokers with varying degrees of airflow obstruction during the period between January 1, 1993, and July 1, 2001.

Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort.

A sensitive screening approach for lung cancer could markedly reduce the high mortality rate for this disease. Previous studies have shown that methylation of gene promoters is present in exfoliated cells within sputum prior to lung cancer diagnosis. The purpose of the current study is to conduct a nested case-control study of incident lung cancer cases from an extremely high-risk cohort for evaluating promoter methylation of 14 genes in sputum.

Multi-target interphase fluorescence in situ hybridization assay increases sensitivity of sputum cytology as a predictor of lung cancer.

Survival rates for lung cancer are low because patients have disseminated disease at diagnosis; therefore tests for early diagnosis are highly desirable. This pilot study investigated occurrence of chromosomal aneusomy in sputum from a 33 case-control cohort matched on age, gender, and date of sample collection. Subjects had chronic obstructive pulmonary disease and > or = 30 pack-years of tobacco use, and aneusomy was tested using a multi-target DNA FISH assay (LAVysion, Abbott/Vysis).

Assessing the role of influential mentors in the research development of primary care fellows.

Purpose: To assess the association between mentorship and both subsequent research productivity and career development among primary care research fellows.

Method: In 1998, using a self-administered questionnaire, the authors surveyed 215 fellows who graduated from 25 National Research Service Award (NRSA) primary care research programs between 1988-1997 to assess quantitative aspects and qualitative domains of their mentorship experience during fellowship training.

Results: A total of 139 fellows (65%) responded to mentorship questions a median of four years after their fellowship.

Podiatric problems are associated with worse health status in persons with severe mental illness.

The objective of this study was to determine the prevalence of self-reported podiatric impairments and their effect on health status in persons with severe mental illness. A sample of psychiatric outpatients (N=309) underwent interviews assessing medical conditions and health status with the Medical Outcomes Study Short Form-36 (SF-36). Podiatric health was assessed using nine items from the National Health Interview Survey (NHIS).

Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction.

Individuals with cytological atypia in sputum may be at increased risk for lung cancer. We conducted a longitudinal analysis of the association between lung cancer incidence and cytological atypia in sputum samples collected prospectively from an ongoing cohort of adults at high risk for lung cancer. Cohort members had a smoking history of > or = 30 pack-years and chronic obstructive pulmonary disease documented by pulmonary airflow testing.

Building capacity for research in family medicine: is the blueprint faulty?

Background And Objectives: This study compared the training programs and career paths of family medicine graduates in the National Research Service Award (NRSA) Program for Research in Primary Medical Care with general internal medicine and general pediatric peers.

Methods: We mailed a survey to NRSA fellows graduating from 23 programs nationally between 1988-1997. Personal characteristics, fellowship experience, current professional activities, and academic productivity were compared among primary care disciplines.

Indicators of early research productivity among primary care fellows.

Objective: Little is known about the impact of fellowship training in primary care on subsequent research productivity. Our goal was to identify characteristics of research fellows and their training associated with subsequent publications and research funding.

Design: Mail survey in 1998.

The training and career paths of fellows in the National Research Service Award (NRSA) Program for Research in Primary Medical Care.

Purpose: To describe the training and career paths of fellows in the National Research Service Award (NRSA) Program for Research in Primary Medical Care.

Method: All fellows who graduated from 25 NRSA programs nationally between July 1988 and June 1997 (n = 215) were mailed a questionnaire. Personal characteristics, fellowship experiences, and current professional positions were compared between faculty researchers, faculty clinician-educators, and individuals who were not in full-time academic positions.