Publications by authors named "Kiara V Whitley"
Article Synopsis
- vB_KquU_φKuK6 is a bacteriophage that infects multidrug-resistant bacterial strains and shows potential for phage therapy despite being a temperate phage.
- The phage's structure includes a complex capsid and a genome with genes essential for lytic and lysogenic infections, along with properties that indicate stability across various conditions.
- While vB_KquU_φKuK6 can reduce biofilm formation and enhance the effectiveness of certain antibiotics, it cannot be used directly for therapy due to its nature but could be valuable when modified or used alongside treatments.
Metabolic function plays a key role in immune cell activation, destruction of foreign pathogens, and memory cell generation. As T cells are activated, their metabolic profile is significantly changed due to signaling cascades mediated by the T cell receptor (TCR) and co-receptors found on their surface. CD5 is a T cell co-receptor that regulates thymocyte selection and peripheral T cell activation.
View Article and Find Full Text PDFSince the completion of the Human Genome Project in 2003, genomic sequencing has become a prominent tool used by diverse disciplines in modern science. In the past 20 years, the cost of genomic sequencing has decreased exponentially, making it affordable and accessible. Bioinformatic and biological studies have produced significant scientific breakthroughs using the wealth of genomic information now available.
View Article and Find Full Text PDFA full semester flow cytometry course improves graduate and undergraduate student confidence.
Biochem Mol Biol Educ
March 2020
Flow cytometry is a versatile and high throughput technique for rapid and efficient biological testing. It requires a high level of conceptual, technical, and analytical skills to properly design experiments, effectively operate flow cytometry machines, and analyze the data. A lack of training and development of any of these three skills can result in underutilization and improper use of flow cytometric machines that can impede research progress.
View Article and Find Full Text PDFBacteriophages are a major force in the evolution of bacteria due to their sheer abundance as well as their ability to infect and kill their hosts and to transfer genetic material. Bacteriophages that infect the Enterobacteriaceae family are of particular interest because this bacterial family contains dangerous animal and plant pathogens. Herein we report the isolation and characterization of two jumbo myovirus Erwinia phages, RisingSun and Joad, collected from apple trees.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses the bacterium that causes fire blight, a harmful disease impacting certain plants, particularly apples and pears.
- Researchers isolated bacteriophages, which are viruses that infect bacteria, from samples taken from infected trees in Utah.
- The study presents 19 complete genome sequences of these isolated bacteriophages, highlighting their potential in combating the disease.