[Growth hormone level dynamics in acromegaly in response to glucose load and measured bicycle ergometry].

The work is based on the materials of clinical examination of 67 patients with acromegaly. Study of the hypothalamo-hypophysial reaction in respect to the growth hormone secretion in patients with acromeglay revealed correlation between the clinical picture indicating the progress of the disease and pointing to the activity of the process according to the results of glucose load and dosaged veloergometry test. Dosaged physical exercise can be used to determine the activity of the process in patients with acromegaly accompanied by disturbances of the carbohydrate metabolism when glucose load was contraindicated.

[Study of hemodynamics in patients with acromegaly by means of radiocardiography].

Determination of the indices of central hemodynamics by means of radiocardiography shows them to be essentially changed in patients with acromegaly in the active stage. A clear correlative relationship has been established between the shifts in hemodynamics and the heart volume determined by X-ray. The diagnosis of preclinical stage of circulatory insufficiency is based on revealing a statistically significant increase in the stroke index and a decrease in the circulation volume and total peripheral resistance.