Publications by authors named "Kiah J Farr"
Int J Breast Cancer
November 2020
Article Synopsis
- PILC is a more aggressive form of invasive lobular carcinoma (ILC) linked to the activation of the PI3K/Akt/mTOR pathway, which leads to higher cell proliferation rates.
- In a study, 85% of PILCs exhibited elevated proliferation markers (Ki67) compared to just 20% of ILCs, while differences in markers PTEN and pS6K1 were noted between the two types.
- Gene analysis showed that PILCs overexpress genes related to cell cycle activation and repair, indicating they have distinct biological characteristics that may necessitate different therapeutic approaches.
