Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health.

Purpose: Delayed rod-mediated dark adaptation (DA) is characteristic of early age-related macular degeneration (AMD) and also can be observed in some older adults in normal macular health. We examine cross-sectional associations between rod-mediated DA and risk factors for AMD in older adults in normal macular health.

Methods: The sample consisted of adults aged ≥60 years old in normal macular health per grading of fundus photos using an established disease classification system.