Publications by authors named "Ki Hyun Kim"

Diet digestibility can vary based on factors such as the type of ingredients, processing techniques, formulation, fiber content, and nutrient interactions. Unlike proteins and fats, there is no specific carbohydrate requirement, which typically constitutes 30%-60% of commercial dried dog foods. Because of the significant proportion of carbohydrates in dog food, this study aimed to evaluate the differences in nutrient digestibility among barley, brown rice, corn, mung bean, and rice, which are common carbohydrate sources in commercial dog foods.

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The present study aimed to investigate the immunostimulatory activities of polysaccharides purified from Glycyrrhiza glabra root. First, five polysaccharide fractions were separated from G. glabra through hot water extraction, ethanol precipitation, enzymatic hydrolysis, and size exclusion chromatography.

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The photocatalytic degradation (PCD) of toluene (as model aromatic volatile organic compound (VOC)) is studied using two-dimensional semiconductors (bismuth oxyhalides (BiOX (X = Cl and Br)) synthesized with surface defects (BiOX-R (R = reduction)) through a solvothermal-induced reduction process. The PCD efficiency of BiOCl-R against 5 ppm toluene (20 % relative humidity (RH)) is 98.6 % under ultraviolet light irradiation with the quantum yield and clean air delivery rate of 1.

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Two Gram-stain-positive, facultatively anaerobic, non-hemolytic, coccoid-shaped bacterial strains, designated MS01 and MS02, were isolated from cabbage watery kimchi in the Republic of Korea. Cellular growth occurred at 5-25 ℃ (optimum, 20 ℃), pH 5-8 (optimum, pH 7) and in the presence of 0-5% (w/v) NaCl (optimum, 1%). Results of 16S rRNA gene-based phylogenetic analyses showed that strains MS01 and MS02 shared identical sequences, clustered within the Leuconostoc clade in phylogenetic trees, and were most closely related to Leuconostoc inhae IH003 and Leuconostoc gasicomitatum LMG 18811 with sequence similarities of 98.

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, commonly known as the bonnet bellflower or deodeok, is primarily found in Eastern Asia. Its roots have been used traditionally across Asia to treat various ailments such as bronchitis, coughs, asthma, and inflammation. In our ongoing efforts to discover bioactive natural products, a phytochemical investigation of the -BuOH fraction of root extracts led to the isolation and identification of a new indole alkaloid -glycoside, deodeokaloid (D-indole-3-lactic acid -β-D-glucopyranoside) (), alongside known compounds tangshenoside I (), tangshenoside IV (), and chlorogenic acid () through HPLC purification.

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  • CAR-T cells are effective against certain blood cancers but face challenges due to potential toxicity from targeting common tumor antigens that are also found on normal cells.
  • This study presents a solution using switchable CAR-T cells that utilize a tumor-targeting adaptor, allowing for targeted therapy while avoiding damage to healthy cells.
  • The approach shows promise in reducing toxicity and enhancing safety, potentially expanding the types of tumors that CAR-T therapies can effectively treat.
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This research has been carried out to investigate unique relationships in adsorption behavior between polar and non-polar volatile organic compounds (VOCs: formaldehyde (FA) versus toluene) using commercial macadamia nutshell (MNS)-based microporous activated carbon (i.e., Procarb-900: namely, P900).

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  • The study focused on thread lifting, a cosmetic procedure, and tested the effects of using both thicker and thinner threads in different skin layers on 43 patients.
  • Researchers evaluated the outcomes through ultrasonography and patient satisfaction measurements immediately after and six months post-procedure.
  • Results showed that multi-layered thread insertion significantly improved patient satisfaction and aesthetic scores, indicating that this method is more effective than inserting threads in a single layer.
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, commonly known as glasswort, thrives in reclaimed land and coastal areas with high salinity, demonstrating remarkable adaptation to the arid conditions of such environments. Two aerobic, Gram-stain-negative, non-motile, rod-shaped bacterial strains, designated TR-M5 and TR-M9, were isolated from the root of plants. These bacteria exhibit plant growth-promoting and salt tolerance-enhancing abilities, which have not been reported in other species of the genus.

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The practical utility of activated carbon/titanium dioxide (AC/TiO) composite has been investigated for the abatement of a common aromatic volatile organic compound (VOC), toluene. The adsorption and photocatalytic performance of the prepared AC/TiO composites (ACT-x: x as the theoretical mass ratio (in percent) of AC over TiO ranging from 0% to 10%) is evaluated individually against gaseous toluene using a packed flow tube reactor under varying operational conditions (e.g.

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Recently, antimicrobial-resistant pathogens and cancers have emerged as serious global health problems, highlighting the immediate need for novel therapeutics. Consequently, we aimed to isolate and characterize endophytic strains from the rhizospheres of the Himalayan region of Nepal and identify specialized metabolites with antibacterial, antifungal, and cytotoxic potential. To isolate sp.

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A novel Gram-stain-positive, facultatively anaerobic, non-motile, catalase-positive, oxidase-negative and ovoid cocci, designated as A1S7, was isolated from the gut of a marine sandworm (). Strain A1S7 exhibited optimal growth at temperatures of 20-30 ℃, pH 6-8 and in the presence of 2-4% (w/v) NaCl. Phylogenetic analysis based on the 16S rRNA gene sequence indicated that strain A1S7 belonged to the genus , exhibiting a similarity of 99.

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The optimal vaginal microbiome is a Lactobacillus-dominant community. Apart from Lactobacillus iners, the presence of Lactobacillus species is associated with reduced vaginal inflammation and reduced levels of pro-inflammatory cytokines. Loss of Lactobacillus-dominance is associated with inflammatory conditions, such as bacterial vaginosis (BV).

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  • The activity of palladium (Pd) catalysts is influenced by various factors, including the properties of the support material, surface chemistry of metal nanoparticles, and metal-support interactions.
  • A Pd/titanium dioxide (TiO) catalyst was developed for efficient degradation of gaseous toluene, achieving a removal efficiency of 79.6% under specific conditions after high-temperature treatment.
  • The study explored the photocatalytic mechanism for toluene degradation, focusing on the role of reactive oxygen species (ROS) generation and highlighting the potential for designing better photocatalysts through surface defect engineering.
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Human lung cancer carries high genetic alterations, expressing high tumor-specific neoantigens. Although orthotopic murine lung cancer models recapitulate many characteristics of human lung cancers, genetically engineered mouse models have fewer somatic mutations than human lung cancer, resulting in scarce immune cell infiltration and deficient immune responses. The endogenous mouse lung cancer model driven by Kras mutation and Trp53 deletion (KP model) has minimal immune infiltration because of a scarcity of neoantigens.

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  • ERCP is a complex medical procedure that improves access but can lead to serious complications, emphasizing the need for quality management to ensure safety.
  • The Korean Society of Pancreatobiliary Endoscopy created a set of quality indicators specifically for ERCP in Korea, based on observations from foreign standards and expert reviews.
  • This tailored approach aims to enhance the overall quality and safety of ERCP procedures in the country, addressing local medical environments and needs.
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Alopecia, while not life-threatening, significantly impacts mental health, identity, and self-esteem of those afflicted. Current pharmacological and surgical treatments often have side effects and are limited in their ability to regenerate hair follicles (HF). Therefore, effective solutions for alopecia remain elusive.

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Anthropogenic emissions of greenhouse gases (GHG; , CO) are regarded as the most critical cause of the current global climate crisis. To combat this issue, a plethora of CO capture, utilization, and storage (CCUS) technologies have been proposed and developed based on a number of technical principles (, post-combustion capture, chemical looping, and catalytic conversion). In this light, the potential utility of dendritic fibrous nanosilica (DFNS) materials is recognized for specific CCUS applications (such as adsorptive capture of CO and its catalytic conversion into a list of value-added products (, methane, carbon monoxide, and cyclic carbonates)) with the highly tunable properties (, high surface area, pore volume, multifunctional surface, and open pore structure).

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  • Rice exhibits beneficial properties, including antioxidant and anti-inflammatory effects, making it a valuable plant for cosmetics and pharmaceuticals.
  • The study focused on using rice callus extracts, developed with the 2,4-D hormone, to inhibit melanoma cell growth and enhance skin whitening.
  • Results showed that rice callus extracts, particularly the aqueous version, are more effective than arbutin in reducing melanin production, suggesting their potential use in skin-lightening products.
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  • PT, a unique tree native to Korea, has strong anti-inflammatory properties, making it a potential natural therapeutic agent.
  • The study isolated nine compounds, including two new flavonoids, and found that the ethyl acetate fraction effectively reduced various free radicals.
  • PT extracts showed low toxicity in macrophages and significantly decreased the expression of proinflammatory proteins, suggesting its effectiveness in treating inflammation-related disorders and emphasizing the need for more research.
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The isolation of a natural product conventionally precedes its chemical synthesis. Often, the isolation and structure determination of a natural product present in minute quantities in its natural source pose formidable challenges, akin to finding "a needle in a haystack." On the other hand, leveraging plausible biosynthetic insights and biomimetic synthetic expertise would allow for the prior synthesis of presumed natural products, followed by their verification in natural sources.

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This study investigates the impact of intravenous (IV) infusion protocols on the stability of Intravenous Immunoglobulin G (IVIG) and Rituximab, with a particular focus on subvisible particle generation. Infusion set based on peristaltic movement (Medifusion DI-2000 pump) was compared to a gravity-based infusion system (Accu-Drip) at different flow rates. The impacts of different diluents (0.

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The genus Salix spp. has long been recognized as a healing herb for its use in treating fever, inflammation, and pain relief, as well as a food source for its nutritional value. In this study, we aimed to explore the potential bioactive natural products in the leaves of Salix chaenomeloides, commonly known as Korean pussy willow, for their protective effects against skin damage, including aging.

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A prototype air purifier (AP) module has been constructed using bismuth-doped titanium dioxide (Bi-P25: x(%) as Bi/Ti molar ratios of 1.1, 2.1, 3.

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  • Calcinosis cutis has five types (dystrophic, metastatic, idiopathic, iatrogenic, calciphylaxis) and can be misdiagnosed as cancer, making management difficult.
  • A study of 7 patients, treated between 2013-2022, highlighted successful diagnoses and complete mass excisions without significant complications, leading to full recovery.
  • The use of imaging techniques (X-rays, ultrasound, CT, MRI) was crucial for accurate diagnosis and treatment, promoting safer, less invasive procedures and preventing recurrences.
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