Increased CCL2/CCR2 axis promotes tumor progression by increasing M2 macrophages in MYC/BCL2 double-expressor DLBCL.

The pathogenesis of myelocytomatosis oncogene (MYC) and B-cell lymphoma 2 (BCL2) double-expressor diffuse large B-cell lymphoma (DE-DLBCL) remains unclear. To investigate how MYC and BCL2 contribute to tumor aggressiveness, we analyzed tumors from 14 patients each with DE-DLBCL and non-DE-DLBCL using whole transcriptome sequencing. Validation was performed using publicly available data sets, tumor tissues from 126 patients, DLBCL cell lines, and a syngeneic mouse lymphoma model.

Case report: Investigation of genetic mutations in a case of schistosomus reflexus in a Holstein dairy cattle fetus in Korea.

Schistosomus reflexus (SR) is one of the most common congenital anomalies found in cases of cattle dystocia; this disorder occurs mostly in cattle. Congenital anomalies such as SR are caused by various genetic and environmental factors, but no specific cause has been elucidated for SR. This study reports a case of SR in a Holstein dairy cattle fetus with congenital anomalies in Korea.

Clear cell variant mucoepidermoid carcinoma of salivary gland in a grey wolf (Canis lupus).

A 14-year-old male grey wolf (Canis lupus) with a history of severe facial swelling was submitted for necropsy. Clinical and radiological examination demonstrated an expansile neoplastic mass in the nasal and frontal sinuses. On necropsy, an amorphous neoplastic mass and extensive necrosis were observed in the nasal turbinate.

A case of concomitant EGFR/ALK alteration against a mutated EGFR background in early-stage lung adenocarcinoma.

Rare cases of lung adenocarcinoma (LUAD) with concomitant epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocation have been reported. However, their clonal and evolutional relationship remains unclear. We report a case of early-stage EGFR-mutated LUAD with a focal concomitant EGFR/ALK alteration.

Effects of X-ray irradiation on the postharvest quality characteristics of 'Maehyang' strawberry (Fragaria × ananassa).

This study evaluated the effects of X-ray irradiation (0-1 kGy) on quality parameters of Korean strawberries during storage at 15 °C for 9 d. As compared to control, all irradiated samples exhibited dose-dependent decreases in microbial counts regardless of storage period. Irradiation significantly (p < 0.

Rapid Identification Method for Gamma-Irradiated Soybeans Using Gas Chromatography-Mass Spectrometry Coupled with a Headspace Solid-Phase Microextraction Technique.

This study evaluated the applicability of a rapid analytical method using a headspace solid-phase microextraction gas chromatography/mass spectrometry (HS-SPME-GC/MS) technique to identify gamma-irradiated soybeans (0.1-5 kGy). From the partial least squares discriminant analysis used to discriminate between non-irradiated and irradiated soybean samples, 1,7-hexadecadiene was selected as the identifying marker.

Comparison of freeze-drying and hot air-drying on Asian pear ( Nakai 'Niitaka') powder: changes in bioaccessibility, antioxidant activity, and bioactive and volatile compounds.

The bioaccessibility, antioxidant activity, and bioactive and volatile compounds of freeze-dried Asian pear powder (FDAPP) and hot air-dried Asian pear powder (HDAPP) were investigated. Compared to FDAPP, HDAPP exhibited significantly (< 0.05) higher total phenolic, arbutin, and bioaccessible phenolic contents and the ferric reducing ability of plasma for the free phenolic fraction.

Preparation of PS/PVP/TiO₂ Core-Shell Particles Under Various Reaction Factors.

The present study deals with the formation of monodisperse sub-micron sized PS/PVP/TiO₂ core- shell hybrid particles via sol-gel method and the effects of varying concentrations of polystyrene seed latex and TBOT, amount and addition rate of water, and sonication power. These reaction factors were found to be closely related to the final particle size, TiO₂ shell thickness, particle density, refractive index, and thermal properties. The particle densities and the refractive indices of the resulting PS/PVP/TiO₂ core-shell hybrid particles were in the range of 2.

Phytochemical Composition and Antioxidant Activities of Two Different Color Chrysanthemum Flower Teas.

Ramat is a perennial flowering plant widely cultivated for use in a tea infusion and as a popular beverage. To identify and evaluate the tea infusion made with a γ-irradiated mutant chrysanthemum cultivar with dark purple petals (cv. ARTI-Dark Chocolate), its phytochemical composition and antioxidant activity were tested and compared with those of the commercially available chrysanthemum cultivar with yellow petals (cv.

Effects of ultrasonication, agitation and stirring extraction techniques on the physicochemical properties, health-promoting phytochemicals and structure of cold-brewed coffee.

Background: Ultrasonication, agitation and stirring or a combination of ultrasonication, agitation and stirring extraction techniques were applied to observe their effects on the physicochemical properties, health-promoting phytochemicals, and structure of cold brewed coffee.

Results: All the extraction techniques led to significant (P < 0.05) increases in the color values, total soluble solids, antioxidant activities and most organic acids, while a combination of extraction techniques increased the chlorogenic acid and caffeine content significantly (P < 0.

Thoracolumbar Paraspinal Myonecrosis after Aortic Dissection.

Thoracolumbar paraspinal myonecrosis can be developed with various etiologies. It can induce compartment syndrome of spinal muscles and cause elevated pressure on back muscles, resulting in severe back pain. Thoracolumbar paraspinal myonecrosis is a very rare disease.

Physicochemical properties and sensory evaluation of mandarin () beverage powder spray-dried at different inlet air temperatures with different amounts of a mixture of maltodextrin and corn syrup.

This study aimed to investigate the effects of varying mixtures of maltodextrin and corn syrup on the physicochemical characteristics and sensory evaluation results of mandarin beverage powder under different spay drying conditions including inlet air temperature and concentration of carrier agents. Higher inlet air temperatures increase in the a* value, pH, and WSI while decreasing the moisture content, L* value, b* value, vitamin C content, and bulk density. Increasing carrier agent concentration caused increases in the L* value and pH along with decreases in the moisture content, a* value, b* value, WSI, vitamin C content and bulk density.

Preparation of Poly[Styrene(ST)-co-Allyloxy-2-Hydroxypropane Sulfonic Acid Sodium Salt(COPS-I)] Colloidal Crystalline Photonic Crystals.

Colloidal crystalline photonic crystals using highly monodisperse poly[Styrene(ST)-co-Allyloxy-2-hydroxypropane sulfonic acid sodium salt(COPS-I)] microspheres were prepared to study their optical properties under visible light. For this purpose, a series of surfactant-free emulsion copolymerizations was carried out at various reaction conditions such as the changes of ST/COPS-I ratio, polymerization temperature, KPS initiator and DVB crosslinker concentration. All the latices showed highly uniform spherical particles in the size range of 165-550 nm and the respective opaline structural colors from their colloidal photonic crystals.

Monodispersepoly[BMA-co-(COPS-I)] Particles by Soap-Free Emulsion Copolymerization and Its Optical Properties as Photonic Crystals.

In order to study the surfactant-free emulsion copolymerization of benzyl methacrylate (BMA) with sodium 1-allyloxy-2-hydroxypropane sulfonate (COPS-I) and the resulting optical properties, a series of experiments was carried out at various reaction conditions such as the changes of BMA concentration, COPS-I concentration, BMA concentration under a fixed COPS-I amount, initiator and divinyl benzene (DVB) concentration. All the latices showed highly monodispersed spherical particles in the size range of 144~435 nm and the respective shiny structural colors from their colloidal photonic crystals. It is found that the changes in such polymerization factors greatly affect the number of particles and particle diameter, polymerization rate, molecular weight, zeta-potential, and refractive indices.

Membrane photoreactor treatment of 1,4-dioxane-containing textile wastewater effluent: Performance, modeling, and fouling control.

A membrane photoreactor (MPR) system was investigated for the purification of textile wastewater effluent containing 1,4-dioxane for potential reuse. The effects of TiO2 dosage, alkalinity, particulate matter, and sunlight radiation on the removal of 1,4-dioxane from the effluent were evaluated. The photocatalytic 1,4-dioxane degradation followed pseudo-first order reaction kinetics.

Colored polystyrene particles with a surface charge influenced by suspension polymerization.

Blue polystyrene (PS) particles copolymerized with poly (ethylene glycol) ether methyl methacrylate (PEG-MA, Mn = 300, 475, 950) were prepared by suspension polymerization in this study. 0-10 wt% PEG-MA was copolymerized with 100-90 wt% styrene by suspension polymerization. These blue PS particles were characterized using SEM, IR, UV, DSC, and zeta potential measurements.

Preparation of poly(BMA-co-MMA) particles by soap-free emulsion polymerization and its optical properties as photonic crystals.

Narrowly dispersed poly(BMA-co-MMA) and PBMA latices with particle diameters ranging within 216-435 nm were synthesized successfully by surfactant-free emulsion polymerization with KPS and AIBA. The average particle diameter and particle size distribution, average molecular weight and its distribution, glass transition temperature, reflectance spectra in visible wavelength, and refractive indices for the respective poly(BMA-co-MMA) latices and their photonic crystals were systematically investigated in terms of BMA/MMA ratio, BMA content, polymerization temperature, and DVB effect. The rate of polymerization increased with increasing MMA concentration in BMA/MMA ratio.

Surfactant-free, cationic latices of poly(BMA-co-MMA) using AIBA initiator.

When polymer particles come into use, especially, for photonic crystal applications, their diameter, dispersivity, and refractive indices become very important. Poly(benzyl methacrylate) is known to be a kind of high refracive materials (n = 1.57) compared to poly(methyl methacrylate) (n = 1.

Use of an aortic stent graft extension for the treatment of urethral stricture in a dog.

A 2-year-old male mixed dog was referred to us for further evaluation and treatment of a 4-week-history of oliguria and abdominal distension after a surgical repair of urethral injury. To relieve the urethral stricture, we placed a self-expanding aortic stent graft extension with a partial coverage with an expanded polytetrafluoroethylene (ePTFE). After the placement of the stent, the dog presented with a normal urinary voiding, despite the presence of urinary incontinence.

Effect of topical anesthesia on evaluation of corneal sensitivity and intraocular pressure in rats and dogs.

Objective: To determine the effect of 0.5% proparacaine in tonometry by evaluating corneal touch threshold (CTT) and intraocular pressure (IOP).

Animal Studied:   Nine rats (18 eyes, Sprague-Dawley) and 10 dogs (20 eyes, Beagle)

Procedures: The IOP and CTT were measured in each eye before and after topical anesthesia with 0.

Cytologic and immunohistochemical characterization of a primitive neuroectodermal tumor in the brain of a dog.

A 6-year-old intact female Pointer dog was presented for evaluation of acute onset of ataxia, circling, and head tilt. Neurologic assessment revealed overall decreased postural reaction, left-sided hemiparesis with incoordination, rigidity of fore- and hindlimbs, strabismus of the right eye, and bilateral horizontal nystagmus. Using magnetic resonance imaging, a mass lesion was identified in the cerebrum adjacent to the left side of the cerebellum compressing the brain stem ventrally.

Successful treatment of an unusually large corneal epithelial inclusion cyst using equine amniotic membrane in a dog.

A 10-year-old intact male Yorkshire Terrier was referred for investigation of a large raised and nonpainful corneal lesion oculus dexter. Clinical examination revealed a pale, translucent corneal mass, which occupied half of the corneal surface and measured 11 mm x 11 mm x 13 mm. The mass was removed by superficial keratectomy and equine amniotic membrane (AM) was transplanted into the large corneal defect to cover the wound and provide tectonic support for the remaining cornea.

Electromagnet weight reduction in a magnetic levitation system for contactless delivery applications.

This paper presents an optimum design of a lightweight vehicle levitation electromagnet, which also provides a passive guide force in a magnetic levitation system for contactless delivery applications. The split alignment of C-shaped electromagnets about C-shaped rails has a bad effect on the lateral deviation force, therefore, no-split positioning of electromagnets is better for lateral performance. This is verified by simulations and experiments.

The antitumor effect and hepatotoxicity of a hexokinase II inhibitor 3-bromopyruvate: in vivo investigation of intraarterial administration in a rabbit VX2 hepatoma model.

Objective: The purpose of this study was to compare the antitumor effect and hepatotoxicity of an intraarterial delivery of low-dose and high-dose 3-bromopyruvate (3-BrPA) and those of a conventional Lipiodol-doxorubicin emulsion in a rabbit VX2 hepatoma model.

Materials And Methods: This experiment was approved by the animal care committee at our institution. VX2 carcinoma was implanted in the livers of 36 rabbits.