Rate of central corneal thickness changes in primary angle closure eyes: long-term follow-up results.

Background: Central corneal thickness (CCT) and its association with intraocular pressure, which is a pivotal parameter in glaucoma management, has previously been reported. In this study, we intended to investigate the long-term change of CCT in terms of rate in eyes with primary angle-closure (PAC). Additionally, we aimed to analyze events that could affect CCT.

Peripapillary Microvascular Improvement and Lamina Cribrosa Depth Reduction After Trabeculectomy in Primary Open-Angle Glaucoma.

Purpose: To evaluate peripapillary microvascular changes in patients with primary open-angle glaucoma (POAG) after trabeculectomy using optical coherence tomography (OCT) angiography, and to determine the influence of lamina cribrosa (LC) displacement on changes in peripapillary microvasculature.

Methods: The peripapillary retinal microvasculature and LC were imaged using OCT angiography and OCT-enhanced depth imaging, respectively. The microvasculature and LC depth (LCD) were measured before, and 1 week, 1 month, and 3 months after trabeculectomy.

Diagnostic Ability of Retinal Nerve Fiber Layer Thickness Deviation Map for Localized and Diffuse Retinal Nerve Fiber Layer Defects.

. To evaluate the diagnostic ability of the retinal nerve fiber layer (RNFL) deviation map for glaucoma with localized or diffuse RNFL defects. .

The Effect of Optic Disc Center Displacement on Retinal Nerve Fiber Layer Measurement Determined by Spectral Domain Optical Coherence Tomography.

Purpose: To investigate the effect of optic disc center displacement on retinal nerve fiber layer (RNFL) measurement determined by spectral domain optical coherence tomography (SD-OCT).

Methods: The optic disc center was manipulated at 1-pixel intervals in horizontal, vertical, and diagonal directions. According to the manipulated optic disc center location, the RNFL thickness data were resampled: (1) at a 3.

Retinal Nerve Fiber Layer Thickness Measurement Repeatability for Cirrus HD-OCT Retinal Tracking System During Eye Movement.

Purpose: To investigate the repeatability of peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained using Cirrus high-definition optical coherence tomographic (Cirrus HD-OCT) retinal tracking system during various types of eye movements.

Materials And Methods: We included 20 healthy eyes, 40 glaucomatous eyes of elderly patients, and 17 eyes with pathologic nystagmus. For healthy eyes, RNFL thickness measurements were obtained under 3 conditions: (1) without eye movement, fixated on the device's internal target, (2) with horizontal eye movement, and (3) with vertical eye movement during scan acquisition.

Retinal nerve fiber layer defect volume deviation analysis using spectral-domain optical coherence tomography.

Purpose: To report the retinal nerve fiber layer (RNFL) defect volume deviation according to structural RNFL loss in RNFL thickness maps.

Methods: Retinal nerve fiber layer defect is defined in RNFL thickness maps by the degree of RNFL loss. A 20% to 70% degree of RNFL loss was set with a 1% interval as the reference level for determining the boundary of RNFL defects.

Diffuse retinal nerve fiber layer defects identification and quantification in thickness maps.

Purpose: To report retinal nerve fiber layer (RNFL) defect identification and quantification in RNFL thickness maps according to the structural RNFL loss, and to evaluate diffuse RNFL defects.

Methods: A total of 170 patients with glaucoma and 186 normal subjects were consecutively enrolled. We defined RNFL defects in an RNFL thickness map by the degree of RNFL loss.

Quantitative analysis of localized retinal nerve fiber layer defects using spectral domain optical coherence tomography.

Purpose: To compare the topographic features of localized retinal nerve fiber layer (RNFL) defects presented in red-free RNFL photography and spectral domain optical coherence tomography (SD-OCT), and to evaluate the correlation with structural and functional parameters.

Methods: Sixty eyes with localized RNFL defects in red-free RNFL photographs were included. RNFL thickness map and significance map were obtained by SD-OCT.

Retinal nerve fiber layer volume measurements in healthy subjects using spectral domain optical coherence tomography.

Purpose: To report retinal nerve fiber layer (RNFL) volume measurement using spectral domain optical coherence tomography (SD-OCT). We determined the characteristics and effecting factors of the RNFL volume in healthy eyes.

Methods: Eighty-six eyes from 86 healthy volunteers were included.

TCCR/WSX-1 is a novel angiogenic factor in age-related macular degeneration.

Purpose: Age-related macular degeneration (AMD) is the major cause of blindness among persons aged 60 years and older. The current approved therapies for AMD are exclusively limited to inhibiting vascular endothelial growth factor. However, substantial improvement in vision occurs in only one-third of patients treated with vascular endothelial growth factor antagonists, and one-sixth of treated patients still progress to legal blindness.

Optic disc pit with peripapillary retinoschisis presenting as a localized retinal nerve fiber layer defect.

A 59-year-old woman was referred to our clinic for a glaucoma evaluation. The visual acuity and intraocular pressure were normal in both eyes. However, red-free fundus photography in the left eye showed a superotemporal wedge-shaped retinal nerve fiber layer defect, and visual field testing showed a corresponding partial arcuate scotoma.

A case of optic nerve atrophy with severe disc cupping after methanol poisoning.

We report a rare case of optic nerve atrophy with severe disc cupping resulting from methanol poisoning. A 30-year-old man presented to the hospital complaining of decreased visual acuity in both eyes a day after drinking alcohol containing methanol. His initial visual acuity allowed for only visualizing hand motion and not corrected in either eye.

Comparison of glaucomatous optic nerve damage in primary angle-closure glaucoma with and without acute attack.

Purpose: To compare the glaucomatous optic nerve damage in primary angle-closure glaucoma (PACG) with acute attack (acute PACG; AACG) and PACG without acute attack (chronic PACG; CACG).

Methods: The study subjects were 84 normal individuals, 130 AACG patients, and 86 CACG patients. Color optic disc photographs were evaluated for the presence or absence of 10 qualitative signs to differentiate between normal and glaucomatous optic discs.