High-throughput screening of nano-hybrid metal-organic-frameworks for photocatalytic CO reduction.

Photocatalytic conversion of CO into fuel feed stocks is a promising method for sustainable fuel production. A highly attractive class of materials, inorganic-core@metal-organic-framework heterogeneous catalysts, boasts a significant increase in catalytic performance when compared to the individual materials. However, due to the ever-expanding chemical space of inorganic-core catalysts and metal-organic frameworks (MOFs), identification of these optimal heterojunctions is difficult without appropriate computational screening.

Elucidating Local Structure and Positional Effect of Dopants in Colloidal Transition Metal Dichalcogenide Nanosheets for Catalytic Hydrogenolysis.

Tailoring nanoscale catalysts to targeted applications is a vital component in reducing the carbon footprint of industrial processes; however, understanding and controlling the nanostructure influence on catalysts is challenging. Molybdenum disulfide (MoS), a transition metal dichalcogenide (TMD) material, is a popular example of a nonplatinum-group-metal catalyst with tunable nanoscale properties. Doping with transition metal atoms, such as cobalt, is one method of enhancing its catalytic properties.

Development and usability testing of your MS questionnaire: A patient-based digital tool to monitor symptoms of multiple sclerosis.

Objectives: We describe the development of Your Multiple Sclerosis Questionnaire and present the real-world usability testing results of Your Multiple Sclerosis Questionnaire.

Methods: The Your Multiple Sclerosis Questionnaire tool was developed in four stages to collect feedback from people living with MS (plwMS), patient organizations, and clinicians on content, format, and applicability. To assess its usability, 13 clinicians across 7 countries completed an online survey after using the tool with plwMS in a total of 261 consultations from September, 2020 to July, 2021.

Two edges of the screen: Unpacking positive and negative associations between phone use in everyday contexts and subjective well-being.

A plethora of past studies have highlighted a negative association between phone use and well-being. Recent studies claimed that there is a lack of strong evidence on the deleterious effects of smartphones on our health, and that previous systematic reviews overestimated the negative link between phone use and well-being. In a three-week long in-the-wild study with 352 participants, we captured 15,607 instances of smartphone use in tandem with rich contextual information (activity, location, company) as well as self-reported well-being measures.

Multiple Sclerosis Progression Discussion Tool Usability and Usefulness in Clinical Practice: Cross-sectional, Web-Based Survey.

Background: A digital tool, Multiple Sclerosis Progression Discussion Tool (MSProDiscuss), was developed to facilitate discussions between health care professionals (HCPs) and patients in evaluating early, subtle signs of multiple sclerosis (MS) disease progression.

Objective: The aim of this study is to report the findings on the usability and usefulness of MSProDiscuss in a real-world clinical setting.

Methods: In this cross-sectional, web-based survey, HCPs across 34 countries completed an initial individual questionnaire (comprising 7 questions on comprehensibility, usability, and usefulness after using MSProDiscuss during each patient consultation) and a final questionnaire (comprising 13 questions on comprehensibility, usability, usefulness, and integration and adoption into clinical practice to capture the HCPs' overall experience of using the tool).

Outcomes of distal biceps tendon repair using a dual incision, cortical button technique: a single surgeon study.

Background: The purpose of this study was to evaluate patient-reported outcomes, function, complication rates, and radiographs in a series of patients with distal biceps tendon repair using the dual incision cortical button technique by a single surgeon. By having a single surgeon perform the surgery, the technique is standardized to all patients. Twenty-two patients consented to participate in the study.

How not to miss infective causes of hip pain in children.

A referral from accident and emergency for a child with hip pain is a scenario commonly faced by orthopaedic juniors on call. The list of differentials is vast and can make assessment and diagnosis challenging, with severe consequences if diagnosis is delayed or missed. Three common causes of paediatric hip pain are septic arthritis, transient synovitis and osteomyelitis.

Treatment strategies for osteochondral lesions of the talus: A review of the recent evidence.

Background: There has been no consensus regarding the treatment of osteochondral lesions of the talus, there has been many attempts to formulate a treatment pathway, with multiple proposed modalities and adjuncts used.

Objectives: The aim of this paper was to investigate the evidence published in the recent history, identify the relevant papers, review and summarize the findings, to help clarify the available operative treatment options and their respective efficacies based on the level of evidence provided.

Study Design & Methods: A literature search through electronic databases MEDLINE and EMBASE was done, these databases were screened for publications and papers form June 2004 to June 2019.

Mores of the customer base for ecotourism industry: Development and validation of a new measurement scale.

To date, there is no such scale that may precisely measure mores of the customer base for the ecotourism industry. Therefore, a thematic analysis of literature has been conducted by examining various good quality research works on intrinsic characteristics eliciting pro-environmental actions. Based upon the thematic analysis, a new scale of measure has been proposed with the help of 17 scholars and 15 practitioners hailing from different countries by mutually agreed intended meanings and breadth of the theoretical concepts.

Synthesis of luminescent core/shell α-ZnP/ZnS quantum dots.

Metal chalcogenide nanoparticles offer vast control over their optoelectronic properties via size, shape, composition, and morphology which has led to their use across fields including optoelectronics, energy storage, and catalysis. While cadmium and lead-based nanocrystals are prevalent in applications, concerns over their toxicity have motivated researchers to explore alternate classes of nanomaterials based on environmentally benign metals such as zinc and tin. The goal of this research is to identify material systems that offer comparable performance to existing metal chalcogenide systems from abundant, recyclable, and environmentally benign materials.

Extension of planned behavioral theory to consumer behaviors in green hotel.

This study aims to contribute to the development of an extended theory of planned behavior to understand the indicators of consumer behavior. A conceptual framework highlighting four study constructs (i.e.

A Retrospective Study Comparing Crossed and Lateral Wire Configurations in Paediatric Supracondylar Fractures.

Background: Supracondylar fractures are common in children and are associated with significant morbidity. The purpose of our study was to assess and compare the clinical and radiological outcome of management of supracondylar fractures by both wire configurations, along with identifying factors that predispose to complications.

Materials & Methods: We retrospectively reviewed all paediatric cases admitted with a supracondylar fracture over a five year period.

The Effect of Two Weeks Preoperative Finasteride Therapy in Reducing Prostate Vascularity.

Objective: To determine the effect of two weeks preoperative finasteride therapy in reducing prostate vascularity in terms of mean microvessel density (MVD) and expression of VEGF in prostate urothelium among patients of BPH by comparing with controls.

Study Design: Randomized controlled trial.

Place And Duration Of Study: Shifa International Hospital, Islamabad, from January 2013 to January 2014.

Mercury exposure in the work place and human health: dental amalgam use in dentistry at dental teaching institutions and private dental clinics in selected cities of Pakistan.

During the past two decades, mercury has come under increasing scrutiny with regard to its safety both in the general population and in occupationally exposed groups. It's a growing issue of global concern because of its adverse environmental and health impacts. Very few investigations on mercury amalgam use in the dentistry sector have been carried out in South Asia and there is little data reported on mercury contamination of indoor/outdoor air at dental sites.

Mercury poisoning dentistry: high-level indoor air mercury contamination at selected dental sites.

Mercury (Hg), also known as quick silver, is an essential constituent of dental amalgam. It is a toxic substance of global concern. Children are more at risk from mercury poisoning which affects their neurological development and brain.

Parathyroid carcinoma.

Parathyroid carcinoma is a rare cause of hypercalcaemia due to primary hyperparathyroidism. Ninety five percent of parathyroid carcinomas are functional tumours. Surgery is the only potential curative treatment.

Former DDT factory in Pakistan revisited for remediation: severe DDT concentrations in soils and plants from within the area.

A factory in Amman Garh near Nowshera, Khyber Pakhtunkhwa, Pakistan, produced dichlorodiphenyltrichloroethane (DDT) from 1963-1994. Consequently, earlier papers reported a soil contamination in the per mille range inside the former factory wall (88 m × 106 m) and up to 10 mg/kg of DDT in the surroundings in 2005-2007. The site within the factory wall was remonitored systematically in 2011 to complement the earlier data as a prerequisite for remediation, to put them in exposure context in a population developing area, and to suggest and evaluate the optimal remediation technique for the site.

A randomised controlled trial of a pilot intervention to encourage early presentation of oral cancer in high risk groups.

Objective: Prognosis for oral cancer is substantially improved when diagnosed early. This research aimed to evaluate an intervention to promote early presentation of oral cancer.

Methods: Participants were randomly assigned to a leaflet group (n = 42), a one-to-one group (n = 46) or a control group (n = 24).

Hazardous waste in the Asian Pacific region.

The production and disposal of hazardous waste remains a substantial problem in the Asian Pacific region. Remediation of waste disposal sites, including landfill sites, is attracting considerable research attention within the region. A recognition of the need for community engagement in this process is also growing.

POPs hot spot.

Like other chemicals of the persistent organic pollutant (POP) group, dichlorodiphenyltrichloroethane (DDT), a pesticide, is also persistent in nature and does not readily degrade in the environment by biological, physical, or chemical processes. In view of the known toxicity, accumulative, persistent characteristics, and adverse environmental and health impacts of DDT, an extensive survey of the soil was undertaken in and around a demolished DDT factory at Nowshera, NWFP, to examine DDT levels of the contaminated soil. For the present study, 81 soil samples were collected within a half-kilometer distance from the old gate of the factory and at different depths in eight different directions.

Meeting report: threats to human health and environmental sustainability in the pacific basin.

The coastal zone of the Pacific Rim is home for about one-third of the world's population. Disproportionate growth of Far Eastern economies has produced a disproportionate share of related environmental difficulties. As the region searches for acceptable compromises between growth and environmental quality, its influence on global environmental health is certain to increase.

Genetic variation in comC, the gene encoding competence-stimulating peptide (CSP) in Streptococcus mutans.

The genetic variability in comC, the gene encoding the quorum-sensing molecule, competence-stimulating peptide (CSP) in Streptococcus mutans is reported. Seven comC alleles encoding three distinct mature CSPs were identified among 36 geographically diverse strains, although, compared with Streptococcus pneumoniae, the amount of predicted amino acid sequence variation is low. In agreement with other studies, significant variation was found in the natural competence for DNA uptake in these strains.

Nicotine partially protects against paraquat-induced nigrostriatal damage in mice; link to alpha6beta2* nAChRs.

Epidemiological studies indicate that smoking is a negative, and exposure to pesticides, a positive risk factor for Parkinson's disease (PD). The purpose of this study was to assess the interplay between these two factors in a rodent model of nigrostriatal damage. To approach this, mice were administered nicotine, the agent in smoke implicated in neuroprotection.