Publications by authors named "Khrupkin V"

The results of treatment of 697 patients with different kinds of non-specific pleural empyema and gangrenous lesions of lungs are presented in the article. Need for complex and differentiated treatment of pleural empyema with obligatory use of thoracoscopy is revealed. High efficiency of early thoracoscopic sanitation improving outcomes and length of hospital stay is proved.

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18 patients with complicated forms of intestinal amebiasis were operated on acute appendicitis, liver abscess or total necrotic colitis. Appendectomy, abscess drainage and colon resection were performed respectively. There were no postoperative deaths.

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The results of experimental study of circulatory acute phase response to the gunshot trauma have shown that triggering of pathologic cascade defined as the traumatic shock is attributed to the free radical concentration created by the wounding projectile in the damaged tissues due to injury sphere formation. So the further study of etiology and pathogenesis of combat pathology is required, the results of which will permit to improve considerably the quality of medical aid rendered to the wounded and casualties.

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The affect of gunshot small arms depends on the weight, speed and moment of projectile's inertia, which determine the trajectory of its movement in the object's substance and the degree of braking characterizing the fullness of energy transmission. The experimental investigations on animals show that the mechanism of tissue lesion during the gunshot injuries has a very complex character and includes both the projectile's direct effect and initiation of some physical phenomena leading to significant tissue damage distally from the wound canal.

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The authors have developed a method of assessment of the degree of the enteral insufficiency syndrome (EIS). The method was used in 2006 peritonitis patients on the basis of 42 clinical-laboratory indices expressed by 10 score scale. A formula for establishing the coefficient of EIS is proposed in cases of the absence of all the indices, the average intervals of its possible degrees are shown.

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Main principles which should be followed when choosing the strategy of treatment in patients with deformities of lower extremities are describes. The authors' experience includes 213 patients with deformities of lower extremities, 59 of them were operated upon. Basing on this experience the authors have developed a classification allowing systematization of the methods for correction of deformities of legs.

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Sixty five patients with peritonitis were examined and divided into two groups. The operative intervention in all the patients included transnasal intubation of the small intestine. The basic enteral therapy used in the first group of patients was made with the glucose-saline solution and transition to a balanced polysubstrate mixture "nutrient standard" with the increasing concentration.

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An original method is proposed for treatment of long-standing intractable wounds and trophic ulcers using viable cryopreserved allodermotransplants and a distant air-plasma treatment. The main source of the allodermotransplants is the cadaverous skin. It was shown that the cadaverous skin taken during 17 hours after the donor's death was viable.

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Basing on the analysis of results obtained during the investigation and treatment of 38 patients suspected of pulmonary artery thromboembolism (PAT) the algorithm of measures applied in our hospital was developed. Its purpose was to put the PAT diagnosis and treatment in order. In our investigations the leading treatment method was the regional infusion therapy conducted through the transformation of diagnostic catheterization of pulmonary artery trunk into the treatment intervention.

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The actual problems of advanced post-diploma training of RF AF medical cadres is analyzed in the article. The investigation of paramount directions of military-and-medical education reform was conducted, the data on additional military-and-medical education system were generalized. The present average annual output of all bases of additional education in RF AF system was subjected to analysis.

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The authors describe experimental and clinical (113 patients) data demonstrating the antimicrobial, hemostatic and stimulating the regenerating processes property of the low energy plasma in local treatment of purulent and long-standing wounds and trophic ulcers.

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The article is devoted to the using of gas-current coagulation for treatment of gunshot wounds in experiment. A new technology of physical action on biological tissues allows the simultaneous performing of hemostasis, sterilization of the wound surface, dissection and evaporation of the tissue. The isolation of the wound surface from unfavorable aggressive factors of the environment due to the layer of thermal necrosis results in shortening the 1 phase of the wound process and in earlier development of its second phase.

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Plasma currents of high energy are considered to be very promising in the surgical treatment of modern pathology. The scientists of this country have constructed a portable field surgery apparatus in which a heated atmospheric air assumes a form of a high-temperature thin jet used like a surgeon's scalpel. Experiments and clinical tests proved the efficacy of this microplasmotron that can destroy and coagulate body tissue when treating it with plasma.

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The article is devoted to the local application of high energy plasma flows in the complex treatment of wounds and wound complications. The new technology of physical action upon the biological tissues allows performing dissections, evaporation and carrying on local hemostasis and sterilization of the wound surface simultaneously. The shortening of the first phase of the wound healing process and earlier development of the second phase are due to the "biophysical isolation" of the wound surface by the thermal necrosis layer from unfavorable effects of the external medium.

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