Lung function in preschool children with a history of wheezing measured by forced oscillation and plethysmographic specific airway resistance.

Rationale: Wheezing is common in preschool children, but objective evidence for airway obstruction and its reversibility are rarely available in clinical practice. We assessed whether abnormalities of lung function and bronchodilator response can be detected in preschool children using the forced oscillation technique and measurements of specific airway resistance.

Methods: Fifty-nine children with a history of wheeze and 24 healthy controls aged 3-6 years were recruited.