Spectrum of lymphoma subtypes based on the latest World Health Organization classification in southern Iran from 2000 to 2011.

Lymphoma, both Hodgkin and non-Hodgkin, is one of the most common malignancies, with a distinct subtype distribution throughout the world. A total of 453 lymphoma cases, identified retrospectively from January 2000 to October 2011, were studied to identify the subtype distribution of lymphoma in our center, located in southern Iran, according to the latest WHO classification. The most common sites of involvement of all lymphomas were extranodal (59.

Zimmermann-Laband syndrome: Clinical and cytogenetic study in two related patients.

Background: Zimmermann-Laband Syndrome (ZLS) is an extremely rare autosomal dominant congenital disorder. It is a craniofacial malformation syndrome with predominant intraoral involvement consisting of gingival fibromatosis diffusion in early development. The molecular basis of ZLS is still unknown.

Discrepancy of target sites between clinician and cytopathological reports in head neck fine needle aspiration: Did I miss the target or did the clinician mistake the organ site?

The diagnostic accuracy of fine needle aspiration cytology (FNAC) of head and neck lesions is relatively high, but cytologic interpretation might be confusing if the sample is lacking typical cytologic features according to labeled site by physician. These errors may have an impact on pathology search engines, healthcare costs or even adverse outcomes. The cytology archive database of multiple institutions in southern Iran and Australia covering the period 2001-2011, were searched using keywords: salivary gland, head, neck, FNAC, and cytology.

Malignant adenomyoepithelioma of the breast: a review.

Malignant adenomyoepithelioma (MAME) of the breast is a rare lesion characterized by dual population of epithelial and myoepithelial cells which one or both components show malignant features. We report a case of MAME of the breast in a 46-year-old woman diagnosed by fine-needle aspiration with extensive review of the literature. Classification, clinical presentation, cyto-pathologic, and immunohistochemical features are described.

Spontaneous splenic rupture in melanoma.

Spontaneous rupture of spleen due to malignant melanoma is a rare situation, with only a few case reports in the literature. This study reports a previously healthy, 30-year-old man who came with chief complaint of acute abdominal pain to emergency room. On physical examination, abdominal tenderness and guarding were detected to be coincident with hypotension.

Molecular diagnosis and species identification of mucosal leishmaniasis in Iran and correlation with cytological findings.

Objective: Mucosal leishmaniasis (ML) is a rare destructive disease that mainly affects the mucous membranes of the mouth and nose. The etiologic agent(s) of ML are not well known in the Middle East.

Study Design: Cytologic smears of ML from the mucosal lesions of 7 patients were prepared by scraping.

Problem of foreign body in GI tract.

Most foreign bodies pass through the gastrointestinal tract uneventful. We report of a case of inadvertently ingested foreign body, which by endoscopy simulated a polyp and on biopsy reported as cancer, so the patient underwent an unnecessary major operation. This report emphasizes the importance of resemblance of foreign bodies with gastrointestinal neoplasm, and endoscopists, surgeons and pathologists should consider this entity in their daily practice.

Clinical, histopathologic, and cytologic diagnosis of mucosal leishmaniasis and literature review.

Context: Mucosal leishmaniasis (ML) is a rare disease in the world, even in endemic areas such as Iran. Clinical, histologic, or cytologic assessment may help in the diagnosis of ML.

Objective: To describe clinical, histologic, and cytologic findings in ML.

Primary bilateral Burkitt lymphoma of the lactating breast: a case report and review of the literature.

Burkitt lymphoma (BL) is a highly aggressive neoplasm, which frequently affects the ileocecal region in the sporadic form and the jaw in the endemic form; however, the breast is a rare primary site of this tumor. Here we describe a case of primary bilateral breast BL presenting during lactation in a 23-year-old woman. Excisional biopsy of breast masses demonstrated a B-cell lymphoma with a characteristic 'starry sky' pattern highly suggestive of BL.

Preoperative washing cytology in the diagnosis of maxillary sinus lesions.

Objective: To assess the preoperative value of washing cytology in maxillary sinus lesions with suspected malignancy.

Study Design: Over a 4-year period, 96 p tients with clinical or radiologic suspicion of a malignant maxillary sinus tumor either confined to the maxillary complex or extending to the nasal cavity underwent preoperative cytologic evaluation by sinus puncture and local washing or nasal washing. Subsequently all patients underwent endoscopic sinus surgery (ESS) and partial or total maxillectomy.

Bone marrow aspiration findings in kala-azar.

Objective: To describe the bone marrow aspiration cytologic findings in visceral leishmaniasis.

Study Design: Bone marrow aspiration of 204 documented cases of kala-azar were reviewed in order to find aspiration clues other than typical intrahistiocytic and free Leishman-Donovan bodies. Aspiration findings were divided into different groups of common, uncommon as well as atypical/unusual findings.

Diagnostic difficulties in the interpretation of fine needle aspirate samples in salivary lesions: diagnostic pitfalls revisited.

Objective: To present our experience in diagnostic errors and pitfalls on aspiration cytology of salivary region in a high volume of cases.

Study Design: In a retrospective review of cytology files of a head and neck referral center from 1990 to 2005, the false positive and false negative interpretations on fine needle aspiration (FNA) of salivary lesions were retrieved. These records and slides were reviewed to identify cytologic characteristics that contributed to false diagnosis.

Cytologic differentiation of struma ovarii from other ovarian neoplasms.

Objective: To present the cytologic findings of struma ovarii and value of cytology and immunocytochemistry (ICC) using thyroglobulin (TGB) and thyroid transcription factor-1 (TTF-1) in evaluation of this unusual ovarian neoplasm, together with the diagnostic pitfalls.

Study Design: Intraoperative cytologic findings of 7 patients with struma ovarii are reviewed. Cytologic material of both cystic and solid components was collected intraoperatively.

Epithelial myoepithelial carcinoma of the parotid gland with malignant ductal and myoepithelial components arising in a pleomorphic adenoma: a case report with cytologic, histologic and immunohistochemical correlation.

Background: To describe the cytologic, histologic and immunohistochemical findings of a case of epithelial myoepithelial carcinoma (EMC) arising from a pleomorphic adenoma (PA) of the parotid with both malignant epithelial and myoepithelial components.

Case: A 29-year-old female presented with a 1.5 x 1.

New cytologic clues in localized Leishmania lymphadenitis.

Objective: To describe new cytologic clues to diagnose localized leishmania lymphadenitis (LLL).

Study Design: The study examined cytologic smears of 170 cases of LLL referred to our department from November 1989 to October 2004. A total of 120 cases were confirmed by detecting Leishman-Donovan (LD) bodies in at least 1 of the cytologic smears and 50 cases, which were histologically confirmed.

Dirofilaria repens diagnosed by the presence of microfilariae in fine needle aspirates: a case report.

Background: Dirofilariasis due to Dirofilaria repens with viable microfilariae outside the worm have not been reported before.

Case: A 40-year-old truck driver from rural Shiraz, Iran, had a firm mass, 2.5 x 2.

Exfoliative cytologic findings of primary pulmonary adenoid cystic carcinom: a report of 2 cases with a review of the cytologic features.

Background: Adenoid cystic carcinoma is a very rare primary pulmonary neoplasm. Cytologic findings of pulmonary washing and brushing in 2 cases of primary bronchial adenoid cystic carcinoma with special histologic features are described, with an emphasis on some points that have not been reported previously, together with the diagnostic pitfalls.

Cases: Two cases of primary adenoid cystic carcinoma of the lung were diagnosed on exfoliative cytology.

Metastatic ganglioneuroblastoma in head and neck diagnosed by fine needle aspiration: a case report.

Background: To describe the cytologic findings of a case of ganglioneuroblastoma metastatic to the jaw and neck.

Case: A 15-year-old boy with a known case of ganglioneuroblastoma of the kidney for the previous 10 years manifested by right mandibular and neck masses on 2 occasions 1 year apart was diagnosed with metastatic ganglioneuroblastoma by fine needle aspiration (FNA). FNA showed neurofibrillary material, small malignant cells, Homer-Wright rosettes.