[Retracted: [THE CONTRIBUTION OF GABA-ERGIC INHIBITION TO THE VELOCITY TUNING OF THE SUPERIOR COLLICULUS NEURONS]].

The formation of selective sensitivity to the movement of the environment at different velocities still remains an unsolved problem. It is assumed that the basis of the creation of such sensitivity can be as processes of inhibition and facilitation at different levels of the visual system. We studied the role of GABA-ergic inhibition in shaping the velocity tuning by affecting GABA antagonist iontophoresis, bicuculine on responses that occur in 80 neurons of the superior colliculus (SC) on the movement of the light spot at 5-45 degrees/s in hamsters anesthetized by urethane.

Dopamine modulation of glutamate metabotropic receptors in conditioned reaction of sensory motor cortex neurons of the cat.

The dopamine modulation of microiontophoretic application of antagonists of glutamate metabotropic synaptic transmission was studied in the sensory motor cortex of awake cats during instrumental conditioned reflex. The substances depressed the background and intensity of evoked impulse activity of pyramidal neurons of the sensory-motor cortex and provoked significant increases in the latency of impulse reaction and corresponding conditioned movements of animals. Simultaneous application of the antagonists and dopamine (DA) eliminated their depression of the background and evoked activity of neurons and decreased the latency of the impulse reactions and movements.

The effects of activation of glutamate ionotropic connections of neurons in the sensorimotor cortex in a conditioned reflex.

Changes in conditioned reflex spike activity of neurons in the sensorimotor cortex were studied during microiontophoretic application of agonists and antagonists of glutamate and GABAergic transmission. The results of these experiments showed that the glutamate ionotropic receptors (AMPA and NMDA) of neurons in the sensorimotor cortex were intensely activated by the arrival of a conditioned signal in the cortex. This response included not only large pyramidal neurons of the deep cortical layers, but also the surrounding inhibitory interneurons.

Dopamine modulation of activity of cat sensorimotor cortex neurons during conditioned reflexes.

The effects of iontophoretic application of dopamine and selective D1 or D2 dopamine receptor agonists and antagonists on impulse activity of neurons of the deep layers of the sensorimotor cortex of cat were investigated during performance of a conditioned paw movement task. The application of dopamine, Quinpirole (selective D2 receptor agonist) or SKF 38393 (selective D1 receptor agonist) increased both background (P<0.001) and evoked impulse activity (P<0.

[Activation of glutamate ionotropic connections of sensorimotor cortex neurons during conditioning].

Changes in conditioned impulse reactions of neurons in sensorimotor cortex were studied during microiontophoretic application of glutamatergic and GABA ergic agonistic and antagonistic drugs. It was shown that ionotropic glutamate receptors (AMPA and NMDA) are activated by a conditioned stimulus. Not only large pyramidal neurons of deep cortical layers but surrounding short-axon inhibitory interneurons are involved in the reaction.

[Place of "Ukrainskogo biokhimicheskogo zhurnal" (Ukrainian Biochemical Journal) in the world information flow in the field of biochemistry].

A comparative statistical analysis of scientific publications of "Ukrainian Biochemical Journal" (UBJ), Biokhimiya (Biochemistry USSR), "Biochemistry" USA has been made. Information analysis was based on the data of annual reference publication "Journal Citation Reports" (JCR) and lists of bibliographic citation in the papers of UBJ and Biokhimiya in 1981, 1986 and 1991. It is found out that as to the composition of publications cited by the UBJ and "Biochemistry" USSR and frequency of their use the journals coincide more frequently than each of them (by this index) coincides with "Biochemistry" USA, that evidences for the difference of the use of information files.

[An analysis of the scientific publications of the A. A. Bogomolets Institute of Physiology of the Academy of Sciences of Ukraine].

Scientific publications from three sectors of the Institute have analyzed for the period since 1979 till 1988 inclusive. The analysis is based on data of annual reference books Science Citation Index (SCI) and lists of publications of each researcher of the Institute. It is shown that with almost equal numerical strength of researchers and similar number of publications the sector of molecular physiology contributed 43.

[Interaction of reactions induced by acoustic and somatosensory stimuli in neurons of the magnocellular portion of the medial geniculate body].

Interaction between impulse activities evoked by a click and contralateral forepaw electrical stimulation was studied in 78 neurons of magnocellular part of the medial geniculate body in cats immobilized with myorelaxine. Among the studied neurons 33 responded by impulse activity both to a click and forepaw stimulation, 25--exclusively to a click and 20--only to stimulation of the forepaw or spinal cord dorsal funiculus. Conditioning stimulation produced inhibition of impulse responses to test stimulus in 32 neurons and only in one neuron facilitation was observed.

[Effect of electrocutaneous stimulation on responses of neurons in the parvocellular portion of the medial geniculate body induced by acoustic stimulation].

The effect of contralateral forepaw electrical stimulation on responses evoked by a click in neurons of the parvocellular part of the medial geniculate body was studied in cats anesthetized by thyopental sodium and immobilized with myorelaxine. Neurons in which responses to a click were inhibited by conditioning forepaw stimulation were located in areas of the parvocellular part of the medial geniculate body adjoining the ventro-posterior nucleus and the magnocellular part of the medial geniculate body. Forepaw stimulation did not affect the neurons located in lateral area of the parvocellular part of the medial geniculate body.

[Responses of the neurons of the magnocellular portion of the medial geniculate body to acoustic and somatosensory stimulation].

The responses of 150 neurons of the magnocellular division of the medial geniculate body (MGB) to sound click and to contralateral forepaw electrical stimulation were studied in cats immobilized with myorelaxine. 68% of the studied neurons had bimodal responses, 16.6% of neurons responded only to click, and 15.